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. 2020 Jan 22;143(2):597–610. doi: 10.1093/brain/awz413

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© The Author(s) (2020). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For permissions, please email: journals.permissions@oup.com

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Mendelian randomization associations of genetic determinants of blood lipid levels (HDL-C, LDL-C, triglycerides) with risk of intracerebral haemorrhage. Shown are the results derived from random-effects inverse-variance weighted (IVW) Mendelian randomization and multivariable Mendelian randomization (MVMR) analyses. MVMR for cholesterol in HDL particles adjusted for LDL-C and triglycerides; for cholesterol in LDL and larger particles adjusted for HDL-C and triglycerides; and for triglycerides in any particles adjusted for HDL-C and LDL-C. TG = triglycerides.