Table B.2.
Results for incidences of megalocytic hepatocytes
Model | Number of parameters | Log‐ likelihood | AIC | Accepted AIC | BMDL | BMDU | BMD | Converged |
---|---|---|---|---|---|---|---|---|
null | 1 | −52.80 | 107.60 | NA | NA | NA | NA | |
full | 7 | −26.17 | 66.34 | NA | NA | NA | NA | |
two.stage | 3 | −28.95 | 63.90 | yes | 0.337 | 1.840 | 0.51 | yes |
log.logist | 3 | −29.43 | 64.86 | no | NA | NA | NA | yes |
Weibull | 3 | −28.42 | 62.84 | yes | 0.038 | 0.656 | 0.24 | yes |
log.prob | 3 | −29.35 | 64.70 | no | NA | NA | NA | yes |
gamma | 3 | −28.22 | 62.44 | yes | 0.018 | 0.607 | 0.19 | yes |
logistic | 2 | −30.09 | 64.18 | yes | 1.090 | 2.200 | 1.50 | yes |
probit | 2 | −30.18 | 64.36 | yes | 1.120 | 2.100 | 1.50 | yes |
LVM: Expon. m3‐ | 3 | −28.39 | 62.78 | yes | 0.047 | 1.290 | 0.26 | yes |
LVM: Hill m3‐ | 3 | −28.69 | 63.38 | yes | 0.0423 | 1.610 | 0.27 | yes |
AIC: Akaike information criterion; BMD: benchmark dose; BMDL: benchmark dose lower confidence limit; BMDU: benchmark dose upper confidence limit; NA: not applicable.