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Genotoxicity data (in vivo) considered by the Panel
| Register name [FL‐no] | End‐point | Test system | Concentration | Results | Reference | Remarks |
|---|---|---|---|---|---|---|
|
Hex‐2(trans)‐enal [05.073] |
Micronucleus induction | Human buccal mucosa cells | 10 mg/kg | Positive | Dittberner et al. (1997) |
Valid Statistically significant increases in micronuclei were observed on days 4, 5, 6 and 7 post‐administration |
