| Lines of evidence | Influence on conclusiona |
|---|---|
| Line of Evidence 1 – animal studies | ↑↑↑ |
| Line of Evidence 2 – information on effects in humans | ↑/↑↑ |
| Line of Evidence 3 – information on mode of action | ↑/↑↑ |
| Line of Evidence 4 – evidence of adverse effects in companion animals | ↑/↑↑ |
| CONCLUSION on whether melamine has the capability to cause adverse effects on kidney in humans | Very likely (90–100% probability) |
a
Key to symbols: ↑, ↑↑, ↑↑↑ represent minor, intermediate and strong upward influence on probability, respectively. Pairs of symbols (↑/↑↑) represent variation of judgements between assessors.