Statistical significance of trends over 4‐5 or more years was tested by a logistic regression model (p ≤ 0.05). Statistically significant increasing trends were observed for ampicillin in Belgium, Denmark, France and Poland, for ciprofloxacin in Finland, France, Hungary, Poland and Switzerland, for cefotaxime in France, as well as for tetracycline in Poland.
Statistically significant decreasing trends were observed for ampicillin in Austria, Germany, Hungary, the Netherlands, Norway and Spain, for ciprofloxacin in Austria, Croatia, the Netherlands, Norway and Spain, for cefotaxime in Belgium, Croatia, Germany, the Netherlands, Poland and Spain, for nalidixic acid in Belgium and the Netherlands, as well as for tetracycline in Austria, Belgium, Croatia, France, Germany, the Netherlands, Spain and Switzerland.