Table C.1.

(Q)SAR predictions on mutagenicity for 13 aldehydes from subgroup 1.1.4

FL‐no JECFA‐no	EU register name	Structural formulaa	ISS local model Ames Test TA100b	MultiCASE Ames testc	MultiCASE mouse lymphoma testd	MultiCASE chromosomal aberration test in CHOe	MultiCASE chromosomal aberration test in CHLf
05.101 1173	Penta‐2,4‐dienal		POS	OD	OD	NEG	NEG
05.057 1175	Hexa‐2(trans),4(trans)‐dienal		POS	POS	OD	NEG	NEG
05.084 1179	Hepta‐2,4‐dienal		POS	EQU	OD	NEG	NEG
05.127 1181	Octa‐2(trans),4(trans)‐dienal		POS	EQU	OD	NEG	NEG
05.071 1185	Nona‐2,4‐dienal		POS	EQU	OD	NEG	NEG
05.173	Nona‐2,4,6‐trienal		NEG	EQU	OD	NEG	NEG
05.081	2,4‐Decadienal		POS	NEG	OD	NEG	NEG
05.140 1190	Deca‐2(trans),4(trans)‐dienal		POS	NEG	OD	NEG	NEG
05.141	Deca‐2,4,7‐trienal		NEG	EQU	OD	NEG	NEG
05.108 1195	Undeca‐2,4‐dienal		POS	EQU	OD	NEG	NEG
05.196	tr‐2,tr‐4‐Undecadienal		POS	EQU	OD	NEG	NEG
05.125 1196	Dodeca‐2,4‐dienal		POS	EQU	OD	NEG	NEG
05.064 1198	Trideca‐2(trans),4(cis),7(cis)‐trienal		NEG	EQU	OD	NEG	NEG

CHO: Chinese hamster ovary; CHL: Chinese hamster lung.

^aStructure group 1.1.4: α,β‐unsaturated aliphatic aldehydes with one or more conjugated double‐bonds.

^bLocal model on aldehydes and ketones, Ames TA100. (NEG: Negative; POS: Positive; OD: out of domain).

^cMultiCase Ames test (OD: Out of domain; POS: Positive; NEG: Negative; EQU: Equivocal).

^dMultiCase Mouse lymphoma test (OD: Out of domain; POS: Positive; NEG: Negative; EQU: Equivocal).

^eMultiCase Chromosomal aberration in CHO (OD: Out of domain; POS: Positive; NEG: Negative; EQU: Equivocal).

^fMultiCase Chromosomal aberration in CHL (OD: Out of domain; POS: Positive; NEG: Negative; EQU: Equivocal).