Table 2.
Parameter symbols used for GUTS modelling in this chapter, explanation and units
| Symbol | Explanation | Example Unit |
|---|---|---|
| Dw | Scaled damage, referenced to external concentration | mol/L |
| Di | Scaled damage, referenced to internal concentration | mol/kg |
| Cw | External chemical concentration in the environment | mol/L |
| Ci | Internal chemical concentration in an organism | mol/L |
| kD | Dominant rate constant for the reduced model | day−1 (or time−1) |
| kin | Uptake rate constant for chemicals into the body | L/kg d−1 |
| kout | Elimination rate constant for chemicals from the body | day−1 |
| kR | Damage repair rate constant | day−1 |
| h | Cumulative hazard rate | day−1 |
| b | Killing rate constant | [D]/day−1 |
| bi | Killing rate constant referenced to internal concentration | kg/mol d−1 |
| bw | Killing rate constant referenced to external concentration | L/mol d−1 (or time−1) |
| z | Threshold for effects | [D] |
| zi | Threshold for effects referenced to internal concentration | mol/kg |
| zw | Threshold for effects referenced to external concentration | mol/L |
| hb | Background hazard rate | day−1 |
| mi | Median of the distribution of thresholds, ref. to internal conc. | mol/kg |
| mw | Median of the distribution of thresholds, ref. to external conc. | mol/L |
| β | Shape parameter for the distribution of thresholds | [−] |