Substance	Type of overall ADI	Overall ADI (μg/kg bw)
Agents acting on the nervous system
Azaperone	Pharmacological	0.8
Cabergoline	Toxicological	0.03
Carazolol	Pharmacological	0.1
Clenbuterol hydrochloride	Pharmacological	0.0042
Detomidine	Pharmacological	0.3
Romifidine	Pharmacological	0.05
Isoxuprine	Pharmacological	2
Agents acting on the reproductive system
Alfaprostol	Toxicological	1
Altrenogest	Pharmacological	0.2
Azagly‐nafareline	Toxicological	0.25
Chlormadinone	Pharmacological	0.07
Cloprostenol	Pharmacological	0.075
Dinoprost tromethamine	Pharmacological	0.83
Flugestone acetate	Pharmacological	0.03
Luprostiol	Toxicological	0.2
Medroxyprogesterone acetate	Pharmacological	0.3
Norgestomet	Pharmacological	0.01
Tiaprost	Toxicological	1.2
Corticoids
Beclomethasone dipropionate	Pharmacological	0.04
Betamethasone	Toxicological	0.015
Dexamethasone	Toxicological	0.015
Methylprednisolone	Pharmacological	0.16
Prednisolone	Pharmacological	0.2
Anti‐infectious agents
Acetylisovaleryl‐tylosin	Microbiological	1.02
Apramycin	Microbiological	40
Avilamycin	Toxicological	115
Bacitracin	Microbiological	3.9
Baquiloprim	Toxicological	10
Cefacetrile	Microbiological	3.5
Cefalexin	Microbiological	54.4
Cefalonium	Microbiological	15.3
Cefapirin	Microbiological	2.54
Cefazolin	Microbiological	10
Cefoperazone	Microbiological	2.5
Cefquinome	Microbiological	3.8
Ceftiofur	Microbiological	20
Chlortetracycline	Microbiological	3
Clavulanic acid	Toxicological	50
Colistin	Microbiological	5
Danofloxacin	Toxicological	24
Difloxacin	Toxicological	10
Dihydro‐streptomycin	Toxicological	25
Doxycycline	Microbiological	3
Enrofloxacin	Microbiological	6.2
Erythromycin	Microbiological	5
Florfenicol	Microbiological	10
Flumequine	Microbiological	8.25
Gamithromycin	Toxicological	10
Gentamicin	Microbiological	4
Kanamycin	Microbiological	8
Lincomycin	Microbiological	10
Marbofloxacin	Microbiological	4.5
Mecillinam	Microbiological	23.8
Monensin	Pharmacological	3.45
Nafcillin	Microbiological	4.4
Neomycin (including framycetin)	Toxicological	60
Novobiocin	Microbiological	1.25
Octenidine dihydrochloride	Toxicological	0.625
Oxolinic acid	Microbiological	2.5
Oxytetracycline	Microbiological	3
Paromomycin	Microbiological	25
Pirlimycin	Microbiological	6
Rifaximin	Microbiological	2
Sarafloxacin	Microbiological	0.4
Spectinomycin	Microbiological	40
Spiramycin	Microbiological	50
Streptomycin	Toxicological	25
Tetracycline	Microbiological	3
Thiamphenicol	Microbiological	2.5
Tiamulin	Toxicological	30
Tildipirosin	Toxicological	100
Tilmicosin	Microbiological	4
Trimethoprim	Microbiological	4.2
Tulathromycin	Microbiological	11
Tylosin	Microbiological	6
Valnemulin	Microbiological	7.95
Virginiamycin	Microbiological	21
Anti‐inflammatory agents
Acetylsalicylic acid	Pharmacological	8.3
Carprofen	Toxicological	10
Diclofenac	Toxicological	0.5
Firocoxib	Toxicological	0.215
Flunixin	Toxicological	6
Ketoprofen	Pharmacological	5
Meloxicam	Toxicological	1.25
Metamizole	Pharmacological	10
Paracetamol	Pharmacological	50
Sodium salicylate	Toxicological	500
Tolfenamic acid	Toxicological	10
Vedaprofen	Toxicological	1.25
Antiparasitic agents
Abamectin	Toxicological	2.5
Albendazole	Toxicological	5
Alphacypermethrin	Toxicological	15
Amitraz	Toxicological	3
Amprolium	Toxicological	100
Azametiphos	Toxicological	25
Clazuril	Toxicological	50
Clorsulon	Toxicological	1
Closantel	Toxicological	30
Coumafos	Toxicological	0.25
Cyfluthrin	Pharmacological	3
Cyhalothrin	Toxicological	5
Cypermethrin	Toxicological	15
Cyromazine	Toxicological	20
Decoquinate	Toxicological	75
Deltamethrin	Toxicological	10
Derquantel	Toxicological	1
Diazinon	Toxicological	2
Diclazuril	Toxicological	30
Dicyclanil	Toxicological	420
Diflubenzuron	Toxicological	12.4
Doramectin	Toxicological	0.5
Emamectin	Toxicological	1
Eprinomectin	Toxicological	5
Febantel	Toxicological	7
Fenbendazole	Toxicological	7
Fenvalerate	Toxicological	12.5
Fluazuron	Toxicological	43
Flubendazole	Toxicological	12
Flumethrin	Toxicological	1.8
Furalaner	Toxicological	10
Halofuginone	Toxicological	0.3
Hexaflumuron	Toxicological	5
Imidocarb	Toxicological	10
Ivermectin	Toxicological	10
Lasalocid	Toxicological	2.5
Levamisole	Toxicological	6
Lufenuron	Toxicological	15
Mebendazole	Toxicological	12.5
Monepantel	Toxicological	30
Morantel	Toxicological	12
Moxidectin	Toxicological	3
Netobimin	Toxicological	5
Nitroxinil	Toxicological	5
Omeprazole	Toxicological	7
Oxfendazole	Toxicological	7
Oxibendazole	Toxicological	60
Oxyclozanide	Toxicological	30
Permethrin	Toxicological	10
Phoxim	Toxicological	3.75
Piperazine	Toxicological	250
Praziquantel	Toxicological	170
Rafoxanide	Toxicological	2
Sisapronil	Toxicological	1
Teflubenzuron	Toxicological	10
Thiabendazole	Toxicological	100
Toltrazuril	Toxicological	2
Triclabendazole	Toxicological	1.5
Others
Bituminosulfonates	Toxicological	1650
Bromhexine	Toxicological	5
Bromide (sodium, potassium)	Toxicological	400
Bronopol	Toxicological	20
Butafosfan	Toxicological	600
Butorphanol tartrate	Toxicological	300
Butylscopolaminium bromide	Pharmacological	10
Chlorhexidine	Toxicological	5
Clodronic acid	Toxicological	50
Dembrexine	Toxicological	20
Denaverine hydrochloride	Toxicological	30
Enilconazole	Toxicological	25
Fenpipramide	Toxicological	1
Furosemide	Pharmacological	2.5
Hydrochlorthiazide	Toxicological	25
Isoeugenol	Toxicological	75
Melatonin	Pharmacological	4
Menbutone	Toxicological	60
1‐Methyl‐2‐pyrrolidone	Toxicological	250
Natamycin	Toxicological	60
Parconazole	Toxicological	80
Piperonilbutoxide	Toxicological	200
Policresulen	Toxicological	1000
Sodium‐2‐fenoxy‐2‐methylpropanoate	Toxicological	100
Tiludronic acid	Toxicological	21
Toldimfos	Toxicological	100
Trichlormethiazide	Toxicological	5
Vetrabutinehydrochloride	Toxicological	15
Vincamine	Pharmacological	9

ADI: acceptable daily intake; bw: body weight; TSV: toxicological screening value.