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. 2018 Aug 7;16(8):e05365. doi: 10.2903/j.efsa.2018.5365
Design Citation Tier Vitamin D dose Age Urinary Ca/Cr ratio
(μg/day) (weeks) unit (mean) (SD)
RCT Holmlund‐Suila et al. (2012) 2 10 13 mmol/mmol 2 n.a.
30 12 mmol/mmol 1.95 n.a.
40 13 mmol/mmol 2.1 n.a.
Gallo et al. (2013a) 1 10 0 othera 1.9 n.a.
10 4 othera 1.6 n.a.
10 8 othera 1.7 n.a.
10 21 othera 1.7 n.a.
10 34 othera 0.9 n.a.
10 48 othera 0.85 n.a.
20 0 othera 2.2 n.a.
20 4 othera 2.1 n.a.
20 8 othera 1.85 n.a.
20 21 othera 1.7 n.a.
20 34 othera 0.8 n.a.
20 48 othera 0.5 n.a.
30 0 othera 1.9 n.a.
30 4 othera 2.1 n.a.
30 8 othera 2 n.a.
30 21 othera 1.6 n.a.
30 34 othera 0.6 n.a.
30 48 othera 0.85 n.a.
40 0 othera 1.7 n.a.
40 4 othera 1.9 n.a.
40 8 othera 2.1 n.a.
40 21 othera 1.6 n.a.
PROSP Hoppe et al. (1997) 3 12.5 0 mol/mol 0.1 0.41
12.5 0 mol/mol 0.22 0.48
12.5 9 mol/mol 0.27 0.87
12.5 9 mol/mol 0.36 0.6
Czech‐Kowalska et al. (2012) 2 16.75b 0 mg/mg 0.46 0.53
16.75b 11 mg/mg 0.57 0.28
12.5c 0 mg/mg 0.39 0.27
12.5c 11 mg/mg 0.61 0.7

PROSP: prospective cohort study; RCT: randomised controlled trial; SD: standard deviation.

The values of urinary Ca/Cr ratio from the study by Siafarikas et al. (2011) not included as the unit was not reported in the paper.

a

outside of the normal range of the hospital (Section 3.3.2.2).

b

vitamin D deficient subjects (Section 3.3.2.3).

c

vitamin D insufficient subjects (Section 3.3.2.3).