Design | Citation | Tier | Vitamin D dose | Age | Urinary Ca/Cr ratio | ||
---|---|---|---|---|---|---|---|
(μg/day) | (weeks) | unit | (mean) | (SD) | |||
RCT | Holmlund‐Suila et al. (2012) | 2 | 10 | 13 | mmol/mmol | 2 | n.a. |
30 | 12 | mmol/mmol | 1.95 | n.a. | |||
40 | 13 | mmol/mmol | 2.1 | n.a. | |||
Gallo et al. (2013a) | 1 | 10 | 0 | othera | 1.9 | n.a. | |
10 | 4 | othera | 1.6 | n.a. | |||
10 | 8 | othera | 1.7 | n.a. | |||
10 | 21 | othera | 1.7 | n.a. | |||
10 | 34 | othera | 0.9 | n.a. | |||
10 | 48 | othera | 0.85 | n.a. | |||
20 | 0 | othera | 2.2 | n.a. | |||
20 | 4 | othera | 2.1 | n.a. | |||
20 | 8 | othera | 1.85 | n.a. | |||
20 | 21 | othera | 1.7 | n.a. | |||
20 | 34 | othera | 0.8 | n.a. | |||
20 | 48 | othera | 0.5 | n.a. | |||
30 | 0 | othera | 1.9 | n.a. | |||
30 | 4 | othera | 2.1 | n.a. | |||
30 | 8 | othera | 2 | n.a. | |||
30 | 21 | othera | 1.6 | n.a. | |||
30 | 34 | othera | 0.6 | n.a. | |||
30 | 48 | othera | 0.85 | n.a. | |||
40 | 0 | othera | 1.7 | n.a. | |||
40 | 4 | othera | 1.9 | n.a. | |||
40 | 8 | othera | 2.1 | n.a. | |||
40 | 21 | othera | 1.6 | n.a. | |||
PROSP | Hoppe et al. (1997) | 3 | 12.5 | 0 | mol/mol | 0.1 | 0.41 |
12.5 | 0 | mol/mol | 0.22 | 0.48 | |||
12.5 | 9 | mol/mol | 0.27 | 0.87 | |||
12.5 | 9 | mol/mol | 0.36 | 0.6 | |||
Czech‐Kowalska et al. (2012) | 2 | 16.75b | 0 | mg/mg | 0.46 | 0.53 | |
16.75b | 11 | mg/mg | 0.57 | 0.28 | |||
12.5c | 0 | mg/mg | 0.39 | 0.27 | |||
12.5c | 11 | mg/mg | 0.61 | 0.7 |
PROSP: prospective cohort study; RCT: randomised controlled trial; SD: standard deviation.
The values of urinary Ca/Cr ratio from the study by Siafarikas et al. (2011) not included as the unit was not reported in the paper.
outside of the normal range of the hospital (Section 3.3.2.2).
vitamin D deficient subjects (Section 3.3.2.3).
vitamin D insufficient subjects (Section 3.3.2.3).