Table A.4.
Summary outcomes of systematic review of experimental infections of domestic animals with WNV (papers published up to January 2016)
| Species | References | Number of animal groupsa | Agent detectionb | Observation of clinical signsc | Clinical signs (and number of groups in which were reported) | ||
|---|---|---|---|---|---|---|---|
| Min day | Max day | Min day | Max day | ||||
| Cats | Austgen et al. (2004) | 3 (19 animals) | Virus isolation from blood: 1 (0.5–3) | Virus isolation from blood: 7 (4.5–8) | 1 | 6 | No clinical signs observed (2), fever (1), depression/apathy (1) |
| 0 dead animals | |||||||
| Dogs | Austgen et al. (2004), Karaca et al. (2005) | 2 (19 animals) | Virus isolation from blood: 1.3 (0.5–2) | Virus isolation from blood: 5.3 (4.5–6) | 1 | 1 | No clinical signs observed (1), fever (1) |
| 0 dead animals | |||||||
| Horses | Bunning et al. (2002), Shirafuji et al. (2009), Castillo‐Olivares et al. (2011) | 4 (17 animals) | Virus isolation from blood (3 groups): 3(1–4) | Virus isolation from blood (3 groups): 6 (6–7) | 6.5 (3–8) | 10 (9–11) | No clinical signs observed (1), twitching/tremors (1), neurological signs (2), fever (1) |
| PCR from blood (1 group): 3 | PCR from blood (1 group): 7 | 1 dead animal in 1 group | |||||
| Pigs | Teehee et al. (2005) | 2 (12 animals) | Virus isolation from blood: 1.5 (1.5–4.5) | Virus isolation from blood: 5 (4.5–5) | Not reported | No clinical signs observed (1), not reported (1) | |
| 0 dead animals | |||||||
| Rabbits | Suen et al. (2015) | 2 (27 animals) | Not reported | 1 | Not reported | No clinical signs observed (1), fever (1) | |
| 0 dead animals | |||||||
| Sheep | Barnard and Voges (1986) | 1 (2 animals) | Virus isolation from blood: 3 | Virus isolation from blood: 11 | 3 | 3 | Fever |
ll data were analysed at animal group level, reflecting the animal groups followed and reported in the individual references. Some references reported more than one animal group.
Min = first day (in dpi) that pathogen/RNA was detected in a sample for each reported animal group; Max = last day (in dpi) that virus/RNA was detected in a sample for each reported animal group. Min and Max were recorded individually for each animal group, and median (min‐max) for each of those values were calculated from all group data (each group representing one observation, with no weighting based on the size of the animal groups). Contact transmission groups were not included in the summary.
Min = first day (in dpi) in which clinical signs were observed in each whole animal group reported; Max = last day (in dpi) in which clinical signs were observed in each whole animal group reported. Min and Max were recorded individually for each animal group, and median (min‐max) for each of those values were calculated from all group data (each group representing one observation, with no weighting based on the size of the animal groups). Contact transmission groups were not included in the summary.