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Outcome of testing of Ames positive chemicals in UDS in vivo and other in vivo genotoxicity assays
| In vivo genotoxicitya | |||
|---|---|---|---|
| UDS | Positive | Negative | Total |
| Positive | 40 | 4 | 44 |
| Negative | 26 | 41 | 67 |
| Total | 66 | 45 | 111 |
| Overall concordance | 73.00% | ||
In either mammalian erythrocyte MN, CA, TGR or comet assays.
UDS: unscheduled DNA synthesis.
