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. 2017 Sep 5;15(9):e04977. doi: 10.2903/j.efsa.2017.4977
ADI 0.025 mg/kg bw per day (EFSA, 2010)
Highest IEDI, according to EFSA PRIMo

Scenario EU1: 130.1% ADI (NL, child)

Scenario EU2: 40.7% ADI (FR, toddler)

Assumptions made for the calculations

Scenario EU1:

The calculation is based on the median residue levels in the raw agricultural commodities, except for bananas, citrus fruits and melons. For bananas, the relevant peeling factor was applied. For citrus fruits, the median value is directly derived from residue levels measured in pulp.

For melons, sweet peppers/bell peppers and for commodities of poultry origin, where data were insufficient to derive a MRL, EFSA considered the existing EU MRL for an indicative calculation. For melons, the relevant peeling factor was applied to the EU MRL

For all plant commodities, the conversion factor from enforcement to risk assessment (CF) of 1 is considered. For animal commodities, the indicative CF derived from the metabolism studies are taken into account

The contributions of commodities where no GAP was reported in the framework of this review were not included in the calculation

Scenario EU2:

Fall‐back GAPs were considered for oranges and grapefruits (post‐harvest waxing) and potatoes (seed treatment). For apples and pears however, no fall‐back option was identified (all other GAPs do also lead to exceedances of the ARfD). Residue levels in livestock commodities were recalculated accordingly. All other input values remain unchanged

ARfD 0.05 mg/kg bw (EFSA, 2010)
Highest IESTI, according to EFSA PRIMo

Scenario EU1:

1414.6% ARfD (potatoes)

685.8% ARfD (apples)

637.5% ARfD (pears)

221.2% ARfD (bovine liver)

183.0% ARfD (oranges)

123.1% ARfD (grapefruits)

Scenario EU2:

76.8% ARfD (mandarins)

Assumptions made for the calculations

Scenario EU1:

The calculation is based on the highest residue levels in the raw agricultural commodities, except for bananas, melons and citrus fruits. For bananas, the relevant peeling factor was applied. For citrus fruits, the highest value is directly derived from residue levels measured in pulp.

For melons, sweet peppers/bell peppers and for commodities of poultry origin, where data were insufficient to derive a MRL, EFSA considered the existing EU MRL for an indicative calculation. For melons, the relevant peeling factor was applied to the EU MRL.

For all plant commodities, the conversion factor from enforcement to risk assessment (CF) of 1 is considered. For animal commodities, the indicative CF derived from the metabolism studies are taken into account

The contributions of commodities where no GAP was reported in the framework of this review were not included in the calculation

Scenario EU2:

Fall‐back GAPs were considered for oranges and grapefruits (post‐harvest waxing) and potatoes (seed treatment). For apples and pears however, no fall‐back option was identified (all other GAPs do also lead to exceedances of the ARfD). Residue levels in livestock commodities were recalculated accordingly. All other input values remain unchanged

CXL: codex maximum residue limit; ADI: acceptable daily intake; bw: body weight; IEDI: international estimated daily intake; PRIMo: Pesticide Residues Intake Model; MRL: maximum residue level; GAP: good agricultural practice; ARfD: acute reference dose; IESTI: international estimated short‐term intake.