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. 2017 Sep 5;15(9):e04977. doi: 10.2903/j.efsa.2017.4977
ADI 0.025 mg/kg bw per day (EFSA, 2010)
Highest IEDI, according to EFSA PRIMo

Scenario CX1: 408% ADI (DE, child)

Scenario CX2: 45.7% ADI (FR, toddler)

Assumptions made for the calculations

Scenario CX1:

For those commodities having a CXL higher than the EU MRL proposal, median residue levels applied in the EU2 scenario were replaced by the median residue levels derived by JMPR. When the median residue level derived by JMPR was not available, the CXL was considered for an indicative calculation. The peeling factor was not considered for citrus fruits and bananas.

The same conversion factors from enforcement to risk assessment (CF) as applied in the EU scenario were considered (CF of 1 for plant commodities and indicative CF derived from the metabolism studies for animal commodities)

Scenario CX2:

The CXLs for potatoes, oranges, grapefruit, pome fruits and persimmon were excluded from the calculation. All other input values remain unchanged.

ARfD 0.05 mg/kg bw (EFSA, 2010)
Highest IESTI, according to EFSA PRIMo

Scenario CX1:

1538% ARfD (potatoes)

1326% ARfD (oranges)

980% ARfD (apples)

911% ARfD (pears)

892% ARfD (grapefruits)

147% ARfD (quinces)

131% ARfD (persimmon)

121% ARfD (medlar)

Scenario CX2:

76.8% ARfD (mandarins)

Assumptions made for the calculations

Scenario CX1:

For those commodities having a CXL higher than the EU MRL proposal, highest residue levels applied in the EU2 scenario were replaced by the median residue levels derived by JMPR. When the highest residue level derived by JMPR was not available, the CXL was considered for an indicative calculation. The peeling factor was not considered for citrus fruits and bananas.

The same conversion factors from enforcement to risk assessment (CF) as applied in the EU scenario were considered (CF of 1 for plant commodities and indicative CF derived from the metabolism studies for animal commodities)

Scenario CX2:

The CXLs for potatoes, oranges, grapefruits, pome fruits and persimmon were excluded from the calculation. All other input values remain unchanged.

CXL: codex maximum residue limit; ADI: acceptable daily intake; bw: body weight; IEDI: international estimated daily intake; PRIMo: Pesticide Residues Intake Model; MRL: maximum residue level; GAP: good agricultural practice; ARfD: acute reference dose; IESTI: international estimated short‐term intake.