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. 2017 Mar 8;15(3):e04698. doi: 10.2903/j.efsa.2017.4698

Table E.1.

Data on EU approved active substances that are to be used for controlling the vectors species, for which midges are included under the target species

Active substance (product type) Target species Intended uses Application/dose rate (i.e. efficacyb) Hazard statements (According to Reg. No 1272/2008a) Risk characterisation ratios (According to REG No 528/2012, Annex VI) Assessment report (link)
Bacillus thuringiensis subsp. israelensis Serotype H14, Strain AM65‐52 (18) Larvae of mosquitoes (Aedes spp., Culex spp) and black flies + larvae of filter fly midges in sewage treatment plants

Ground application: tractor‐mounted or handheld sprayer

Aerial application: fixed wing or helicopter

Applied during the first to the 4th larval instar

 Rates up to 500 g/ha (9 × 1012°CFU/ha) (mortality greater than 95% of the control was observed after 48 h)

Limited survival in the environment

Limited risk to human health, related only to the possibility to induce sensitisation, based on the results obtained on animal models

 EED/PNED ratio** at local level below 1 indicates NO risk for the environment http://dissemination.echa.europa.eu/Biocides/ActiveSubstances/0005-18/0005-18_Assessment_Report.pdf
Deltamethrin (18) Indoors: flying insects when at rest (e.g. flies and mosquitoes), black ants, bedbugs, fleas, earwigs, carpet beetles, booklice and cockroaches, as well as spiders and woodlice. Outdoors: ants Indoors: spray applications, professional users only. Outdoors: directly around the nest entrance, by amateurs

6.25 mg/a.s per m2 (1 month‐low‐dose rate)**

12.5 mg/a.s per m2 (3 months‐high‐dose rate)**

 H400/410: Aquatic Chronic. H331/H301:Acute tox 3,

Aquatic compartment:

  • 1
    Surface water
    1. NO risk if following use in crack and crevice treatments in domestic houses and larger buildings.
    2. RISK if following barrier treatment in domestic houses and larger buildings.
  • 2
    Sediment:
    1. NO risk if for sediment dwelling organisms following use in crack and crevice treatments in domestic houses and larger buildings
    2. RISK if following barrier treatment in domestic houses and larger buildings
Terrestrial compartment:
  1. Soil: NO risk
  2. Groundwater: NO risk
http://dissemination.echa.europa.eu/Biocides/ActiveSubstances/0024-18/0024-18_Assessment_Report.pdf
Lambda‐cyhalothrin (18) Flies and other insects in and around animal housing For fly control, application is as a low‐pressure spray in areas where flies congregate or settle such as floors, walls, ceilings and around doors and windows. For other insects, the product is applied as a low‐pressure spray as a crack and crevice treatment 25 mg/a.s. per m2

H400/410: Aquatic Chronic

H312: Harmful in contact with skin

H301 or H300: toxic or Fatal/if swallowed

H330: Fatal if inhaled

Aquatic compartment:

  1. Sewage Treatment Plant: NO risk
  2. Surface water:
    1. RISK for aquatic organisms at the representative uses of lambda‐cyhalothrin in Demand/ICON 10CS that result in emissions to STP.
    2. RISK: aquatic organisms at the indoor use of OXYFLY 10CS in animal houses (poultry) connected to STP
    3. NO risk For aquatic organisms exposed via distribution of manure/slurry to arable land/grassland
 http://dissemination.echa.europa.eu/Biocides/ActiveSubstances/0041-18/0041-18_Assessment_Report.pdf
Permethrin (18) Flying insects (e.g. flies and mosquitoes) and crawling insects (e.g. roaches, mites, fleas and ticks) Indoor use (households* and commercial areas), by professional and non‐professional users against flying and crawling insects. Spot treatments 0.000011 mg/a.s. per m2 H410 (Acute Cat 1; Chronic Cat 1): Very toxic to aquatic life with long lasting effects. H317: May cause an allergic skin reaction
  • 1

    STP: NO risk

  • 2

    Surface waters:

    1. NO risk (If the product is restricted to use in dry cleaned areas)

    2. RISK (if not respected the scenario a)

  • 3

    Sediment:

    1. NO risk (If the product is restricted to use in dry cleaned areas)

    2. RISK (if not respected the scenario a)

  • 4

    Soil (local): NO risk

  • 5

    There is NO risk to wildlife when professional/non‐professional use is restricted to targeted spot applications in dry cleaned areas or the dry cleaning of areas subject to wetting.

  • 6

    Secondary poisoning: NO risk

http://dissemination.echa.europa.eu/Biocides/ActiveSubstances/1342-18/1342-18_Assessment_Report.pdf
N,N‐diethyl‐meta‐toluamide (19) Biting flies, biting midges or black flies (Ceratopogonidae, Simuliidae), chiggers, deer flies, no‐seeums, gnats, horse flies (Tabanidae), mosquitoes (Culicidae), fleas Aerosol spray, direct dermal application NA

H412: Aquatic Chronic 3

H302: Harmful if swallowed

H315: Causes skin irritation

H319: Causes serious eye irritation

 NO risk to any of the environmental compartments http://dissemination.echa.europa.eu/Biocides/ActiveSubstances/0023-19/0023-19_Assessment_Report.pdf
a

Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006.

b

Efficacy of products will be assessed thoroughly at the stage of product authorisation. Moreover the conclusion was reached within the framework of the uses that were proposed and supported by the applicant (see each Assessment Report, Appendix II). Extension of the use pattern beyond those described will require an evaluation at product authorisation level in order to establish whether the proposed extensions of use will satisfy the requirements of Article 5(1) and of the common principles laid down in Annex VI to Directive 98/8/EC.).