. 2017 Oct 25;15(10):e05005. doi: 10.2903/j.efsa.2017.5005

Table 10.

Summary of the BMD analysis, using model averaging

Response variable	Species and sex	BMD₁₀ (mg/kg bw per day)^a	BMDL₁₀ (mg/kg bw per day)^a	BMDU₁₀ (mg/kg bw per day)^a
Cholangiofibrosis after 36 weeks	Male rats	0.3	0.22	0.41
Cholangiofibrosis after 2 years	Male rats	0.11	0.09	0.12
Hepatocellular adenoma or carcinoma; combined data set from Moser et al. (2009) and NTP (1993)	Female mice	2.6	1.84	4.00
Hepatocellular carcinoma; combined data set from Moser et al. (2009) and NTP (1993) Moser et al. (2009) NTP (1993)
	Female mice Female mice	5.72 7.21	4.18 4.82	7.24 9.10
Hepatocellular adenoma or carcinoma; data set from Moser et al. (2009) only	Female mice	2.4	1.45	3.59
Hepatocellular carcinoma; data set from Moser et al. (2009) only	Female mice	5.34	3.45	7.55

For a 5 days per week dosing regimen.