Table B.2.
Evaluation status of hydrolysis products of candidate esters
| FL‐no | EU register name JECFA no | Structural formula | SCF statusa JECFA statusb CoE statusc EFSA status | Structural classd Procedure path (JECFA)e | Comments |
|---|---|---|---|---|---|
| 4‐Hepten‐2‐ol |
|
Not evaluated as flavouring substance | Not in EU‐Register | ||
| Hexadecanoic acid |
|
Not evaluated as flavouring substance | Not in EU‐Register | ||
| 02.022 |
Octan‐2‐ol 289 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 2000a) Category B (CoE, 1992) |
Class I A3: Intake below threshold |
|
| 02.045 |
Heptan‐2‐ol 284 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 2000a) Category B (CoE, 1992) |
Class I A3: Intake below threshold |
|
| 02.079 |
Isopropanol 277 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 2000a) |
Class I A3: Intake above threshold, A4: Endogenous |
|
| 02.098 |
Octan‐3‐ol 291 |
|
Category 2 (SCF, 1995) No safety concern (JECFA, 2000a) |
Class I A3: Intake below threshold |
|
| 02.121 | Butan‐2‐ol |
|
Category 1 (SCF, 1995) |
Class I No evaluation |
|
| 08.001 |
Formic acid 79 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 1999b) Deleted (CoE, 1992) |
Class I A3: Intake below threshold |
|
| 08.002 |
Acetic acid 81 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 1999b) Category A (CoE, 1992) |
Class I A3: Intake above threshold, A4: Endogenous |
|
| 08.005 |
Butyric acid 87 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 1999b) Category A (CoE, 1992) |
Class I A3: Intake above threshold, A4: Endogenous |
|
| 08.007 |
Valeric acid 90 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 1999b) Category A (CoE, 1992) |
Class I A3: Intake below threshold |
|
| 08.008 |
3‐Methylbutyric acid 259 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 1999b) Category A (CoE, 1992) |
Class I A3: Intake below threshold |
|
| 08.009 |
Hexanoic acid 93 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 1999b) Category A (CoE, 1992) |
Class I A3: Intake above threshold, A4: Endogenous |
|
| 08.010 |
Octanoic acid 99 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 1999b) Category A (CoE, 1992) |
Class I A3: Intake above threshold, A4: Endogenous |
|
| 08.011 |
Decanoic acid 105 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 1999b) Category A (CoE, 1992) |
Class I A3: Intake below threshold |
|
| 08.012 |
Dodecanoic acid 111 |
|
Category 1 (SCF, 1995) No safety concern (JECFA, 1999b) Category A (CoE, 1992) |
Class I A3: Intake below threshold |
SCF: Scientific Committee on Food; JECFA: The Joint FAO/WHO Expert Committee on Food Additives; CoE: Council of Europe.
Category 1: Considered safe in use, Category 2: Temporarily considered safe in use, Category 3: Insufficient data to provide assurance of safety in use, Category 4: Not acceptable due to evidence of toxicity.
No safety concern at estimated levels of intake.
Category A: Flavouring substance, which may be used in foodstuffs, Category B: Flavouring substance which can be used provisionally in foodstuffs.
Threshold of concern: Class I = 1,800 μg/person per day, Class II = 540 μg/person per day, Class III = 90 μg/person per day.
Procedure path A substances can be predicted to be metabolised to innocuous products. Procedure path B substances cannot.