Table 7.
Maximised summed exposure for adults and children to congeneric groups in rum ether, based on the APET estimates for rum ether components at maximum reported concentrations
| Congeneric group | Chronic summed maximised APETs (μg/kg bw per day) | Highest Cramer Class identified for the congeneric group | Lowest TTC applicable for the congeneric group (μg/kg bw per day) | |
|---|---|---|---|---|
| Adults | Children | |||
| 1 | 1,529 | 1,907 | III | n.a.a |
| 2 | 20 | 25 | I | 30 |
| 3 | 5.1 | 6.3 | III | n.a. |
| 4 | 0.72 | 0.90 | II | 9 |
| 5 | 7.6 | 9.5 | III | 1.5 |
| 6 | 1.6 | 2.0 | I | 30 |
| 7 | 3.2 | 4.0 | I | 30 |
| 8 | 4.9 | 6.1 | III | 1.5 |
| 9 | 0.46 | 0.57 | II | 9 |
| 10 | 3.1 | 3.8 | III | 1.5 |
| 11 | 2.2 | 2.7 | III | 1.5 |
| 12 | 1.3 | 1.7 | III | n.a. |
APET: added portions exposure technique; bw: body weight; TTC: Threshold of Toxicological Concern.
a
n.a.: not applicable; there is a concern for genotoxicity for one or more constituents in this congeneric group.