Table 6.
Range of acute exposure assessment (average and 95th percentile)a to the sum of T2 and HT2 across European dietary surveys and percentage of subjects above the acute reference doseb
| Age class | Number dietary surveys | Minimum | Median | Maximum |
|---|---|---|---|---|
| Range of average acute exposure (ng/kg bw per day) | ||||
| Infants | 6 | 15.2 (10.1–29.2) | 27.7 | 54.6 (48.5–69.3) |
| Toddlers | 11 | 47.9 (46.1–50.3) | 55.7 | 64.7 (62.3–69.8) |
| Other children | 20 | 35.1 (33.9–36.7) | 46.3 | 62.1 (59.9–64.7) |
| Adolescents | 20 | 15.3 (14.7–16.1) | 28.1 | 39.5 (38.0–41.2) |
| Adults | 22 | 14.4 (14.1–14.7) | 19.9 | 26.5 (25.6–27.6) |
| Elderly | 16 | 13.4 (13.0–13.9) | 17.8 | 23.5 (21.2–26.5) |
| Very elderly | 14 | 14.5 (13.6–15.8) | 18.7 | 20.7 (19.3–22.4) |
| Pregnant women | 1 | –c | –c | 25.7 (24.7–27.0) |
| Lactating women | 1 | –c | –c | 17.3 (16.1–19.0) |
| Range of 95th percentile acute exposure (ng/kg bw per day) | ||||
| Infants | 5 | 73.0 (65.3–81.1) | –d | 170 (152–193) |
| Toddlers | 10 | 110 (101–121) | 142 | 154 (116–222) |
| Other children | 20 | 84.4 (79.1–89.8) | 116 | 140 (130–151) |
| Adolescents | 20 | 36.2 (33.5–39.4) | 73.2 | 100 (92.1–109) |
| Adults | 22 | 38.0 (36.7–39.3) | 49.8 | 68.4 (63.0–75.0) |
| Elderly | 16 | 34.3 (31.8–37.1) | 43.1 | 55.4 (46.7–66.9) |
| Very elderly | 14 | 37.2 (32.4–42.7) | 43.4 | 55.3 (43.9–69.5) |
| Pregnant women | 1 | –c | –c | 72.0 (66.1–78.7) |
| Lactating women | 1 | –c | –c | 50.2 (43.1–57.6) |
| Number dietary surveys | Minimum | Maximum | |
|---|---|---|---|
| Percentage of subjects above the ARfD b | |||
| Infants | 6 | < 0.01 (0–< 0.01) | 0.07 (0.04–0.10) |
| Toddlers | 11 | < 0.01 (0–0.01) | 0.05 (0.03–0.07) |
| Other children | 20 | < 0.01 (0–< 0.01) | 0.03 (0.01–0.05) |
| Adolescents | 20 | < 0.01 (0–0.01) | 0.01 (< 0.01–0.01) |
| Adults | 22 | < 0.01 (0–< 0.01) | < 0.01 (< 0.01–0.01) |
| Elderly | 16 | < 0.01 (0–< 0.01) | < 0.01 (0–0.02) |
| Very elderly | 14 | < 0.01 (0–< 0.01) | < 0.01 (0–0.02) |
| Pregnant women | 1 | –c | < 0.01 (0–< 0.01) |
| Lactating women | 1 | –c | < 0.01 (0–0.02) |
a
With their corresponding confidence intervals (2.5th and 97.5th percentiles).
b
Range of percentage of subjects above the ARfD after 1,000 iterations in each of the dietary surveys and age classes. ARfD = 300 ng/kg bw per day as derived in the 2017 EFSA CONTAM opinion (EFSA CONTAM Panel, 2017).
c
Only one dietary survey available for ‘Pregnant women’ and ‘Lactating women’.
d
Minimum number of six dietary surveys are required to estimate a statistically robust median (EFSA, 2011b).