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. Author manuscript; available in PMC: 2020 Feb 10.
Published in final edited form as: Exp Dermatol. 2002 Apr;11(2):159–187. doi: 10.1034/j.1600-0625.2002.00112.x

Table 1.

Selective functions of the integument

Protection from the environment
 Mechanical, keep the form and internal organs in position and away from damage
 Chemical, internal homeostasis in water and land (barrier)
 Physical: UV (melanocyte on human)
 Keep moist (amphibian) and oily (sebaceous gland)
 To be worn off
 To heal and regenerate (cytokines)
Defense
 Exoskeleton (arthropod)
 Armor (turtle, armadillo)
 Spiny appendages (porcupine quills)
 Inflammatory response (prostaglandin, etc.)
 Immune function, with memory of previous stimuli
Weapons
 Sting cell of hydra and jelly fish
 Claws
 Poisonous glands
Communication with outside organisms
 Display of messages (pigment pattern, painted skin of human)
 To mark territory
 Pheromones for sexual attraction
 For pack behavior coordination
 To scare enemies away
 To mimic
Communication with inside organs
 Sense the environment (human skin, mouse vibrissa)
 Tactile or thermo senses go in through nerves
 Endocrine-like function through secretion (neuro-endocrines, endorphin, growth factors, etc.)
Respiration
 Insects
 Some frogs
Chemical reaction
 Vitamin D
Locomotion
 Swim (tentacles of hydra, jelly fish and octopus; tube feet of sea cucumber)
 Crawl (belly scale of snake)
 Glide (skin flap of Pterosaur, bat)
 Fly (feathers)
Thermoregulation
 Hairs (mammals)
 Sweat gland
 Dermal blood vessels
 Feathers (feathered dinosaurs, birds)
Progeny bearing
 Skin flap in toads and abdominal pouch in kangaroos
 Mammary glands in mammals