Table H.1.

Examples of orally administered formulations commonly available in the EU (information based on product SPCs, non‐exhaustive list)

Class/substance	Indications (based on SPCs)	Route of administration	Dose duration (based on SPCs)
Tetracyclines Oxytetracycline, chlortetracycline, doxycycline	Treatment and metaphylaxis Pigs: respiratory infections, septicaemia, digestive infection Poultry: respiratory infections; septicaemia, digestive infection, infectious bursal disease Calves, Lambs, Kids: respiratory disease, septicaemia, digestive infection Salmon and trout: furunculosis, enteric redmouth	Premix for MFS Oral powders, solutions for drinking water	10 days 3–8 (5) days
Macrolides Tylvalosin, tylosin, tilmicosin, erythromycin, lincomycin	Treatment and metaphylaxis Pigs: enzootic pneumonia (Mycoplasma), PPE (ileitis); swine dysentery; enteritis Poultry: Mycoplasma infections, necrotic enteritis, ORT Rabbits: respiratory diseases	Premix for MFS Oral powder/solutions for drinking water	7 days – 3 weeks in feed, or until clinical signs resolve 3–5 days for powder in feed or drinking water
Sulfonamides/Trimethoprim Sulfadiazine, sulfamethoxazole	Treatment and metaphylaxis Pigs: infections in general Poultry: infections in general Calves, lambs, rabbits and fish	Premix for MFS Oral solutions for drinking water	5–10 days in feed 3–4 (4–7) days for drinking water
Pleuromutilins Tiamulin, valnemulin	Treatment and metaphylaxis Pigs: colitis; swine dysentery; PPE (ileitis); enzootic pneumonia (Mycoplasma) Poultry: respiratory diseases; Mycoplasma infections Rabbits: epizootic rabbit enterocolitis (ERE)	Premix for MFS Oral powder Oral solutions for drinking water	7 days to 4 weeks, or until clinical signs resolve Drinking water administration for 5 days
Penicillins Penicillin V, Amoxicillin Ampicillin	Treatment and metaphylaxis Pigs: respiratory diseases; Streptococcus suis Poultry: respiratory and intestinal infections Calves: respiratory and intestinal infections	Premix for MFS, Oral powders for feed and drinking water	5 days to 2 weeks (up to 6 weeks for Strep. suis) in feed Drinking water administrations for 5 days
Aminoglycosides/aminocyclitols Apramycin, neomycin, streptomycin, spectinomycin	Pigs: bacterial enteritis, enzootic pneumonia (incl Mycoplasma) Calves: colibacillosis, salmonellosis Lambs and Poultry: colibacillosis Poultry: Mycoplasma respiratory infections	Premix for MFS, Oral solution for drinking water	28 days in feed 5–7 days for drinking water
Amphenicols florfenicol	Treatment and metaphylaxis Pigs: respiratory disease Salmon & trout: furunculosis (Aeromonas salmonicida)	Premix for MFS Oral powder in feed Oral solutions for drinking water	5–10 days in feed 5 days for drinking water
Polymyxins Colistin sulfate	Treatment and metaphylaxis Pigs, calves, lambs, poultry: enteric E. coli infections	Premix for MFS Oral solutions in drinking water	3–7 days maximum
Fluoroquinolones Enrofloxacin	Treatment Pigs: respiratory and gastrointestinal infections, septicaemia Calves: respiratory and gastrointestinal infections	Oral solutions for drinking water	3–5 days