Table 56.
Age group(age) | MB exposure estimate from dietc | Urinary DON and glucuronides b | Exposure estimateafrom biomarker | MB exposure estimate from dietc | Urinary DON and glucuronidesb | Exposure estimateafrom biomarker | MB exposure estimate from dietc | Urinary DON and glucuronidesb | Exposure estimateafrom biomarker |
---|---|---|---|---|---|---|---|---|---|
μg/kg bw per day | ng/mL | μg/kg bw per day | μg/kg bw per day | ng/mL | μg/kg bw per day | μg/kg bw per day | ng/mL | μg/kg bw per day | |
UK | Italy | Norway | |||||||
Children (3–9 years) | 1.15 | 21.2 | 0.70 | 1.33 | 8.4 | 0.25 | 1.10 | 10.8 | 0.34 |
Adolescent (10–17 years) | 0.60 | 20.0 | 1.14 | 0.80 | 7.7 | 0.40 | 0.60 | 8.5 | 0.50 |
Adults (18–64 years) | 0.45 | 11.9 | 0.42 | 0.54 | 4.4 | 0.18 | 0.47 | 5.6 | 0.22 |
Elderly (65 years or >) | 0.42 | 8.1 | 0.31 | 0.50 | 4.1 | 0.18 | 0.42 | 4.4 | 0.18 |
Pregnant women | na | 12.2 | 0.42 | na | 1.4 | 0.06 | na | 5.0 | 0.19 |
Vegetarian | na | 10.1 | 0.42 | na | 3.9 | 0.16 | na | 5.1 | 0.22 |
bw: body weight; na: not applicable; MB: middle bound.
Daily exposure is calculated based the DON and glucuronide biomarker and assumption of daily urine volume at 0.5 and 2 L for child and adult, and DON excretion percentage is estimated at 70%.
The individual urinary DON and glucuronide concentrations as ng/mL were extracted from the EFSA database as submitted to EFSA in the DON biomarker project in 2015 (Brera et al., 2015).
The chronic exposures for UK and Italy are the estimates from the diet as presented in this opinion (see Appendix F.1). The food consumption data reported for Denmark were used to compare to the exposure estimate from biomarker in Norway due to the lack of Norwegian food consumption data in the EFSA Comprehensive Food Consumption Database.