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. 2020 Jan 10;56(3):685–696. doi: 10.3892/ijo.2020.4959

Figure 6.

Figure 6

PRC1 expression is regulated by FOXM1. (A) Immunohistochemical staining of PRC1 and FOXM1 in corresponding HGSOC samples. (B) Correlation analysis of FOXM1 and PRC1 from the TCGA chort. (C and E) Western blot analysis and corresponding densitometric analysis were used to examine the expression of PRC1 following FOXM1 knockdown in SKOV3 and A2780 cells. (D) The mRNA expression of PRC1 following FOXM1 knockdown in SKOV3 and A2780 cells was examined by RT-qPCR. (F and G) Luciferase report assay was used to determine the regulatory association between FOXM1 and PRC1. (H and I) Transwell assay was used to examine the effect on the migratory and invasive ability following PRC1 konckdown in A2780 FOXM1-overexpressing cells. **P<0.01.