Table 4. Myf6 RQ-PCR results.
Population | Total | Myf6-positive | Myf6-negative | p-value* | p-value** |
---|---|---|---|---|---|
HCL, non-IGHV4-34 | 147 | 147 (100%) | 0 | <0.0001 | |
HCL, unknown VH | 7 | 7 (100%) | 0 | 1 | <0.0001 |
HCLv, non-IGHV4-34 | 34 | 11 (32%) | 23 (68%) | <0.0001 | 0.0003 |
HCLv, IGHV4-34 | 17 | 7 (41%) | 10 (59%) | <0.0001 | 0.0004 |
HCL, IGHV4-34 | 12 | 11 (92%) | 1 (8%) | 0.076 | <0.0001 |
CLL | 48 | 35 (73%) | 13 (27%) | <0.0001 | <0.0001 |
HCL plus CLL | 3 | 3 (100%) | 0 | 1 | 0.0004 |
Normal donors | 90 | 5 (6%) | 85 (94%) | <0.0001 | |
ATL | 20 | 0 | 20 (100%) | <0.0001 | 0.58 |
MCL | 12 | 1 (8%) | 11 (92%) | <0.0001 | 0.54 |
MZL | 5 | 3 (60%) | 2 (40%) | 0.0009 | 0.0037 |
p-values by Fishers exact compared each group to HCL, non-IGHV4-34 (*) or to normal donors (**). Other comparisons included HCLv, non-IGHV4-34 vs HCLv, IGHV4-34 (p = 0.55), HCLv, IGHV4-34 vs HCL, IGHV4-34 (p = 0.0080), and HCLv, non-IGHV4-34 vs CLL (p = 0.0003).