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. 2020 Feb 10;15(2):e0227586. doi: 10.1371/journal.pone.0227586

Table 4. Myf6 RQ-PCR results.

Population Total Myf6-positive Myf6-negative p-value* p-value**
HCL, non-IGHV4-34 147 147 (100%) 0 <0.0001
HCL, unknown VH 7 7 (100%) 0 1 <0.0001
HCLv, non-IGHV4-34 34 11 (32%) 23 (68%) <0.0001 0.0003
HCLv, IGHV4-34 17 7 (41%) 10 (59%) <0.0001 0.0004
HCL, IGHV4-34 12 11 (92%) 1 (8%) 0.076 <0.0001
CLL 48 35 (73%) 13 (27%) <0.0001 <0.0001
HCL plus CLL 3 3 (100%) 0 1 0.0004
Normal donors 90 5 (6%) 85 (94%) <0.0001
ATL 20 0 20 (100%) <0.0001 0.58
MCL 12 1 (8%) 11 (92%) <0.0001 0.54
MZL 5 3 (60%) 2 (40%) 0.0009 0.0037

p-values by Fishers exact compared each group to HCL, non-IGHV4-34 (*) or to normal donors (**). Other comparisons included HCLv, non-IGHV4-34 vs HCLv, IGHV4-34 (p = 0.55), HCLv, IGHV4-34 vs HCL, IGHV4-34 (p = 0.0080), and HCLv, non-IGHV4-34 vs CLL (p = 0.0003).