Table 1.
Model Parameters
| Symbol | Meaning | Value | Reference |
|---|---|---|---|
| κ | membrane bending modulus | 20 kBT | Rawicz et al., 2000 |
| w | diameter of actin cortex-free zone | 80 nm | Figure 3Aa |
| γPM | PM tension | 0.04 pN nm−1 | Tinevez et al., 2009 |
| εadhesion | membrane-cortex adhesion energy density | 0.02 pN nm−1 | Dai and Sheetz, 1999 |
a
Model solutions with w = 80 nm had ∼30-nm-diameter fusion pores, consistent with the experimental Ω-shapes of Figure 3A. The solutions exhibited a Ω-to-Λ transition at vesicle diameter 56 nm (slightly less than the STED resolution limit), consistent with the finding that 93% of shrink fusion events lacked a visible Λ-sequence in STED measurements.