Table 4. Thermodynamic parameters.
Values in parentheses indicate the standard errors of the mean.
| Ligand | Ligand concentration (µM) | AcAChBP concentration (µM) | No. of sites | K d (µM) | ΔG (kcal mol−1) | ΔH (kcal mol−1) | −TΔS (kcal mol−1) |
|---|---|---|---|---|---|---|---|
| Cytisine (2) (n = 2) | 100 | 20 | 0.6 (0.01) | 0.6 (0.3) | −8.6 (0.3) | −15.2 (1.2) | 6.6 (1.4) |
| 4 (n = 3) | 1000 | 50 | 0.9 (0.10) | 53.3 (19.9) | −6.0 (0.3) | −9.1 (2.5) | 3.0 (2.8) |