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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Gastroenterology. 2019 Oct 22;158(3):527–536.e7. doi: 10.1053/j.gastro.2019.10.019

Table 1.

Comparison of patients with H pylori who did and did not develop gastric cancer

H pylori (n=369,789) H pylori with future non-proximal gastric adenocarcinoma (n = 2,024) P-value
Age in years at H pylori, median (IQR) 62.0 (52.7, 70.9) 65.1 (57.4, 73.3) P<0.001
Male (%) 341,367(92.3%) 1,963 (97.0%) P<0.001
Race (%) P<0.001
 White 214,090 (57.9%) 984 (48.6%)
 Black or African American 87,989 (23.8%) 641 (31.7%)
 American Indian or Alaskan Native 3,322 (0.9%) 17 (0.8%)
 Asian 2,483 (0.7%) 21 (1.0%)
 Native Hawaiian / Pacific Islander 3,837 (1.0%) 13 (0.6%)
 Unknown / Declined to Answer 58,068 (15.7%) 348 (17.2%)
Ethnicity P<0.001
 Hispanic / Latino 290,286 (78.5%) 1,507 (74.5%)
 Not Hispanic or Latino 33,306 (9.0%) 213 (10.5%)
 Unknown / Declined to Answer 46,197 (12.5%) 304 (15.0%)
Ever smoker (%) 97,571 (26.4%) 621 (30.7%) P<0.001
Method of H pylori diagnosis 0.009
 Pathology 26,725 (7.2%) 148 (7.3%)
 Stool Antigen 11,205 (3.0%) 57 (2.8%)
 Urea Breath Test 399 (0.1%) 1 (0.05%)
 RX, no serum Ab 256,883 (69.5%) 1,479 (73.1%)
 ICD, no serum Ab 9,507 (2.6%) 47 (2.3%)
 RX, with serum Ab 7,815 (2.1%) 39 (1.9%)
 ICD, with serum Ab 57,255 (15.5%) 253 (12.5%)
Poverty level of zip code where patient resided at H pylori diagnosis P<0.001
 < 10% residing below poverty level 69,754 (18.9%) 386 (19.1%)
 10 − 24.9% residing below poverty level 184,848 (50.0%) 912 (45.1%)
 25 − 49.9% residing below poverty level 88,986 (24.1%) 572 (28.3%)
 ≥50% residing below poverty level Unknown 9,880 (2.7%) 16,321 (4.4%) 76 (3.8%) 78 (3.9%)
Follow up time in years, median (IQR) 7.4 (3.3, 12.3) 1.8 (0.4,5.8) P<0.001
Deceased 137,575 (37.2%) 1,371 (67.7%) P<0.001

IQR = inter-quartile range; RX = prescription therapy; ICD = International Classification of Diseases (administrative codes); Ab = antibody