Table 1.
H pylori (n=369,789) | H pylori with future non-proximal gastric adenocarcinoma (n = 2,024) | P-value | |
---|---|---|---|
Age in years at H pylori, median (IQR) | 62.0 (52.7, 70.9) | 65.1 (57.4, 73.3) | P<0.001 |
Male (%) | 341,367(92.3%) | 1,963 (97.0%) | P<0.001 |
Race (%) | P<0.001 | ||
White | 214,090 (57.9%) | 984 (48.6%) | |
Black or African American | 87,989 (23.8%) | 641 (31.7%) | |
American Indian or Alaskan Native | 3,322 (0.9%) | 17 (0.8%) | |
Asian | 2,483 (0.7%) | 21 (1.0%) | |
Native Hawaiian / Pacific Islander | 3,837 (1.0%) | 13 (0.6%) | |
Unknown / Declined to Answer | 58,068 (15.7%) | 348 (17.2%) | |
Ethnicity | P<0.001 | ||
Hispanic / Latino | 290,286 (78.5%) | 1,507 (74.5%) | |
Not Hispanic or Latino | 33,306 (9.0%) | 213 (10.5%) | |
Unknown / Declined to Answer | 46,197 (12.5%) | 304 (15.0%) | |
Ever smoker (%) | 97,571 (26.4%) | 621 (30.7%) | P<0.001 |
Method of H pylori diagnosis | 0.009 | ||
Pathology | 26,725 (7.2%) | 148 (7.3%) | |
Stool Antigen | 11,205 (3.0%) | 57 (2.8%) | |
Urea Breath Test | 399 (0.1%) | 1 (0.05%) | |
RX, no serum Ab | 256,883 (69.5%) | 1,479 (73.1%) | |
ICD, no serum Ab | 9,507 (2.6%) | 47 (2.3%) | |
RX, with serum Ab | 7,815 (2.1%) | 39 (1.9%) | |
ICD, with serum Ab | 57,255 (15.5%) | 253 (12.5%) | |
Poverty level of zip code where patient resided at H pylori diagnosis | P<0.001 | ||
< 10% residing below poverty level | 69,754 (18.9%) | 386 (19.1%) | |
10 − 24.9% residing below poverty level | 184,848 (50.0%) | 912 (45.1%) | |
25 − 49.9% residing below poverty level | 88,986 (24.1%) | 572 (28.3%) | |
≥50% residing below poverty level Unknown | 9,880 (2.7%) 16,321 (4.4%) | 76 (3.8%) 78 (3.9%) | |
Follow up time in years, median (IQR) | 7.4 (3.3, 12.3) | 1.8 (0.4,5.8) | P<0.001 |
Deceased | 137,575 (37.2%) | 1,371 (67.7%) | P<0.001 |
IQR = inter-quartile range; RX = prescription therapy; ICD = International Classification of Diseases (administrative codes); Ab = antibody