Table 2.
Risk factors for development of gastric cancer using multivariable competing risk time to event model
| SHR (95% Cl) | P- value | |
|---|---|---|
| Agea | 1.13 (1.11–1.15) | P<0.001 |
| Method of H pylori diagnosis | ||
| Positive diagnostic test | REFERENCE | 0.006 |
| RX, no serum Ab | 0.95(0.82–1.10) | |
| ICD, no serum Ab | 0.89(0.65–1.23) | |
| RX, with serum Ab | 0.83(0.59–1.17) | |
| ICD, with serum Ab | 0.75 (0.62–0.90) | |
| Ethnicity | ||
| Not Hispanic or Latino | REFERENCE | |
| Hispanic or Latino | 1.59(1.34–1.87) | P<0.001 |
| Unknown | 1.30 (1.08–1.55) | |
| Race | ||
| White | REFERENCE | |
| Black or African American | 2.00 (1.80–2.22) | P<0.001 |
| American Indian or Alaskan Native | 1.36(0.84–2.19) | |
| Asian | 2.52(1.64–3.89) | |
| Native Hawaiian or other Pacific Islander | 0.82(0.48–1.42) | |
| Unknown | 1.08(0.91–1.29) | |
| History of smoking | 1.38(1.25–1.52) | P<0.001 |
| Female gender | 0.52 (0.40–0.68) | P<0.001 |
| Poverty level of zip code where patient resided at H pylori diagnosis | ||
| < 10% residing below poverty level | REFERENCE | |
| 10 − 24.9% residing below poverty level | 0.86 (0.77–0.97) | 0.09 |
| 25 − 49.9% residing below poverty level | 0.95(0.84–1.09) | |
| ≥50% residing below poverty level | 0.99(0.76–1.29) | |
| Unknown | 0.83(0.65–1.06) |
a.
Age is per 5-year incremental increase in year
RX = prescription therapy; ICD = International Classification of Diseases (administrative codes); Ab = antibody