Table 2.
Regression coefficients between maternal prepregnancy BMI per 5 unit increments and total hippocampal volume and hippocampal subfield volumes in boys, (N = 37)
| Region | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 |
|---|---|---|---|---|---|
| Hippocampus | |||||
| β (SE) | −134.97 (54.35) | −103.84 (41.94) | −103.55 (42.60) | −113.05 (44.26) | −126.98 (47.26) |
| p‐value | .018* | .018* | .021* | .016* | .012* |
| CA1 | |||||
| β (SE) | −26.88 (11.83) | −21.67 (10.46) | −21.19 (10.46) | −21.57 (10.87) | −23.58 (11.71) |
| p‐value | .029a | .046 | .051 | .057 | .054 |
| CA2/3 | |||||
| β (SE) | −13.20 (4.82) | −11.05 (4.25) | −11.26 (4.24) | −12.44 (4.47) | −14.19 (4.73) |
| p‐value | .010a | .014 | .012 | .009a | .006a |
| CA4 | |||||
| β (SE) | −10.98 (4.67) | −8.38 (3.68) | −8.55 (3.68) | −9.63 (3.92) | −10.34 (4.22) |
| p‐value | .025a | .029 | .026 | .020a | .021a |
| Dentate gyrus | |||||
| β (SE) | −12.30 (5.44) | −9.16 (4.17) | −9.29 (4.21) | −10.36 (4.52) | −11.31 (4.86) |
| p‐value | .030a | .035 | .034 | .029a | .027a |
| Subiculum | |||||
| β (SE) | −13.98 (7.76) | −10.49 (6.81) | −10.17 (6.80) | −11.80 (7.01) | −12.51 (7.58) |
| p‐value | .080 | .13 | .14 | .10 | .11 |
Model 1: unadjusted.
Model 2: adjusted for ICV.
Model 3: adjusted for ICV + child age.
Model 4: adjusted for ICV + child age + SES +maternal gestational diabetes mellitus (GDM) status.
Model 5: adjusted for ICV + child age + SES +maternal GDM status + BMI z‐score.
a
Denotes significance remained after FDR correction for multiple subfields at a threshold of q = 0.05.
*
Significance level at p < .05.