TABLE 2.

The location of the most significant QTLs, limited to the top 5, which were associated with chest width, and the genes located within these QTLs within each breed.

				No of suggestive and significant SNPs	Most significant SNP		Allele frequency of positive allele
Breed	Chr	Start	End			P-Value	AA	CH	HE	LM	SI	HF	Candidate genes within this QTL
Angus	8	19919026	20930648	3	20426751b	4.18 × 10–6	0.057	0.980	0.014	0.896	0.112	0.989	ELAVL2*
	10	101530896	102548539	4	102040999b	5.32 × 10–7	0.232	0.678	0.305	0.306	0.216	0.223	TTC8, FOXN3*
	11	52112729	53133828	13	52632756a	1.85 × 10–6	0.639	0.241	0.895	0.908	0.898	0.105
	12	12006341	13006349	2	12506341a	2.69 × 10–8	0.073	0.047	0.943	0.000	0.918	0.963	VWA8, DGKH, TNFSF11, AKIP11
	28	2715813	4028680	11	3522966d	1.14 × 10–6	0.832	0.806	0.201	0.000	0.808	0.220	SPRTN, TRIM67*
Charolais	3	75099566	76200376	43	75636445b	2.40 × 10–7	0.111	0.071	0.000	0.000	0.903	0.168	CTH, LRRC7*, LRRC40
	9	12560255	13754168	9	13060255a	3.52 × 10–7	0.990	0.016	0.991	0.985	0.987	0.000	MTO1, EEF1A1
	10	42104985	43116388	3	42604985a	3.68 × 10–7	0.003	0.039	0.992	0.948	0.030	0.991	RPL36AL, MGAT2, ARF6, SOS2
	11	10962219	12944023	11	11462219b	3.04 × 10–7	0.000	0.007	0.000	0.000	0.000	0.000	ALMS1, EGR4, SMYD5, CYP26B1, SFXN5*
	18	57584619	58600780	3	58084619d	1.61 × 10–7	0.002	0.012	0.991	0.004	0.031	0.000	ENSBTAG00000014593*
Hereford	4	82061233	83396596	4	82561233a	2.12 × 10–7	0.000	0.989	0.023	0.012	0.994	0.993	POU6F2
	6	38955125	39995325	14	39461621a	6.63 × 10–7	0.308	0.000	0.852	0.000	0.000	0.604	LCORL
	7	79663134	80729587	3	80197062a	8.60 × 10–9	0.013	0.014	0.996	0.000	0.012	0.978
	10	56443792	57546809	7	57025496a	9.84 × 10–8	0.961	0.000	0.967	0.050	0.893	0.062	WDR72
	23	8222426	9377363	9	8722426d	1.37 × 10–7	0.010	0.009	0.005	0.005	0.010	0.979	UHRF1BP1*, HMGA1, NUDT3, SCUBE3
Limousin	1	61741512	63549298	3	63048403a	1.08 × 10–6	0.439	0.000	0.650	0.730	0.449	0.225
	6	37530341	38792617	34	38284104b	1.09 × 10–7	0.298	0.000	0.685	0.565	0.722	0.460	PPM1K, ABCG2*, PKD2*, SPP1, MEPE*, LAP3
	18	9391406	10382598	13	9891406b	1.69 × 10–6	0.211	0.249	0.109	0.137	0.447	0.136	CDH13*, HSBP1, MLYCD
	18	55221720	56247875	3	55721720d	1.39 × 10–6	0.995	0.000	0.002	0.003	0.000	0.000	LIG1, KCNJ14, CYTH2, RPL18, PPP1R15A
	20	7457546	8466248	16	7959103a	9.82 × 10–7	0.057	0.008	0.990	0.987	0.979	0.000	UTP15, ANKRA2
Simmental	13	70061402	71118226	7	70573855a	2.82 × 10–6	0.010	0.050	0.987	0.897	0.055	0.998	TOP1, PLCG1, LPIN3
	23	10151181	11174475	3	10651181b	1.20 × 10–6	0.071	0.913	0.054	0.128	0.068	0.959	CPNE5*, PIM1, TMEM217, TBC1D22B
	23	30033517	31047355	4	30533517c	1.67 × 10–6	0.099	0.072	0.219	0.187	0.902	0.146	ZSCAN31, ZKSCAN4, HIST1H2BB
	25	8699062	9699134	5	9199062a	6.83 × 10–7	0.000	0.000	0.996	0.000	0.005	0.996	EMP2, NUBP1, CLEC16A
	26	48445354	49451650	6	48945354a	2.03 × 10–6	0.989	0.008	0.996	0.041	0.996	0.000
Holstein Friesian	1	57000435	58139976	15	57582901b	7.42 × 10–7	0.034	0.225	0.209	0.688	0.000	0.195	ABHD10, CD200*, ATG3, CCDC80
	2	30344158	31344250	3	30844250a	7.56 × 10–7	0.003	0.000	0.994	0.987	0.998	0.990	TTC21B, GALNT3, CSRNP3
	10	39919494	41220895	5	40476976a	1.04 × 10–6	0.004	0.004	0.975	0.991	0.982	0.861	MDGA3*
	13	78475631	79544490	9	79027846a	9.15 × 10–7	0.059	0.098	0.045	0.765	0.840	0.073	SNAI1, UBE2V1, PTPN1
	24	827290	2268995	9	1331600a	4.86 × 10–7	0.064	0.067	0.986	0.000	0.924	0.013	PQLC1, KCNG2, NFATC1, ATP9B

AA, Angus; CH, Charolais; HE, Hereford; LM, Limousin; SE, Simmental; HF, Holstein-Friesian. Superscript denotes SNP classification:^aintergenic, ^bintron, ^cupstream gene variant, ^ddownstream gene variant. Symbols denote the significance of SNPs within genes: * gene contained at least one suggestive (p ≤ 1 × 10^–5) SNP ^ gene contained at least one significant (p ≤ 1 × 10^–8) SNP.