Table 2.
Enrichment of hypertension by different databases.
| Group | upregulation | downregulation |
|---|---|---|
| Control vs HCMV | ADRB3 ACE PTGIS ERAP1 | RGS5 NOS3 |
| Control vs HG + ox-LDL | ATP1B1 PTGIS | — |
| HCMV vs HG + ox-LDL + HCMV | ATP1B1 RGS5 | CYBA ERAP1 ADRB2 PTGIS |
| HG + ox-LDL vs HG + ox-LDL + HCMV | GRK4 ADRB3 ACE ATP1B1 | RGS5 PTGIS NEDD4L CYBA ERAP1 ADRB2 NPR2 |
Note. Adrenoceptor beta 3(ADRB3); Angiotensin-converting enzyme(ACE); Prostaglandin I2 (prostacyclin) synthase (PTGIS); Endoplasmic reticulum aminopeptidase 1(ERAP1); Regulator of G-protein signaling 5(RGS5), Nitric oxide synthase 3(NOS3); ATPase, Na+/K+ transporting, beta 1 polypeptide(ATP1B1); Cytochrome b-245, alpha polypeptide(CYBA); Endoplasmic reticulum aminopeptidase 1(ERAP1); Adrenoceptor beta 2, surface (ADRB2); G protein-coupled receptor kinase 4(GRK4); Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (NEDD4L); endoplasmic reticulum aminopeptidase 1 (ERAP1); Adrenoceptor beta 2, surface (ADRB2); Selectin E (SELE); Natriuretic peptide receptor 2(NPR2).