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. 2020 Feb 4;10:77. doi: 10.3389/fonc.2020.00077

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Copyright © 2020 Tian, Sun, Liu, Li, Duan, Wang, Fan, Li, Li, Wang, Liu, Tian and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nomogram developed with the combined model and calibration curves, decision curve analysis for the combined model. (A) The developed nomogram. (B) Calibration curve of the combined model in the primary and validation cohorts. The middle gray line represents a perfect prediction. The blue line represents the performance of the combined model. Better prediction is demonstrated by a closer fit of the blue line to the grayline. (C) Decision curve analysis for the combined model. The y-axis depicts the net benefit. The blue line represents the combined model. The grayline represents the assumption that all patients have response of NACT. The black line is the opposite.