Table 4.
Cancer types | Alzheimer's | Vascular dementia | Other dementia | ||||||
---|---|---|---|---|---|---|---|---|---|
O | SIR* | 95% CI | O | SIR* | 95% CI | O | SIR* | 95% CI | |
Oral (upper aerodigestive tract) | 78 | 0.87 | 0.69–1.08 | 65 | 0.70 | 0.54–0.89 | 85 | 0.73 | 0.58–0.90 |
Salivary gland | 18 | 1.76 | 1.04–2.79 | 5 | 0.50 | 0.16–1.18 | 11 | 0.85 | 0.42–1.52 |
Esophageal | 3 | 0.22 | 0.04–0.64 | 4 | 0.28 | 0.07–0.71 | 9 | 0.49 | 0.22–0.93 |
Stomach | 31 | 0.58 | 0.40–0.93 | 34 | 0.59 | 0.41–0.82 | 45 | 0.61 | 0.44–0.81 |
Small intestine | 11 | 0.56 | 0.28–1.01 | 13 | 0.69 | 0.37–1.18 | 22 | 0.94 | 0.59–1.42 |
Colon | 425 | 0.90 | 0.81–0.98 | 348 | 0.74 | 0.67–0.83 | 499 | 0.80 | 0.73–0.87 |
Rectum | 185 | 0.78 | 0.67–0.90 | 160 | 0.65 | 0.56–0.76 | 223 | 0.71 | 0.62–0.81 |
Anus | 8 | 0.63 | 0.27–1.24 | 7 | 0.66 | 0.29–1.37 | 14 | 0.98 | 0.54–1.61 |
Liver | 9 | 0.33 | 0.15–0.63 | 9 | 0.34 | 0.15–0.64 | 16 | 0.47 | 0.27–0.77 |
Pancreas | 1 | 0.05 | 0.00–0.30 | 4 | 0.22 | 0.06–0.58 | 13 | 0.57 | 0.30–0.98 |
Nose | 5 | 0.82 | 0.26–1.92 | 10 | 1.70 | 0.81–3.14 | 6 | 0.75 | 0.27–1.64 |
Lung | 90 | 0.69 | 0.56–0.85 | 65 | 0.55 | 0.42–0.70 | 105 | 0.68 | 0.56–0.83 |
Breast | 824 | 0.91 | 0.85–0.97 | 527 | 0.86 | 0.79–0.94 | 773 | 0.82 | 0.76–0.88 |
Cervix | 20 | 0.74 | 0.46–1.15 | 13 | 0.70 | 0.35–1.15 | 32 | 1.05 | 0.72–1.49 |
Endometrium | 205 | 0.83 | 0.72–0.95 | 144 | 0.78 | 0.66–0.92 | 209 | 0.78 | 0.68–0.90 |
Ovary | 54 | 0.80 | 0.60–1.04 | 22 | 0.46 | 0.29–0.70 | 37 | 0.50 | 0.35–0.69 |
Other female genitals | 19 | 0.82 | 0.49–1.28 | 14 | 0.73 | 0.40–1.22 | 27 | 0.87 | 0.57–1.27 |
Prostate | 1127 | 0.80 | 0.75–0.85 | 1262 | 0.77 | 0.73–0.82 | 1335 | 0.72 | 0.68–0.76 |
Testis | 2 | 0.66 | 0.06–2.44 | 4 | 1.21 | 0.31–3.13 | 6 | 1.71 | 0.62–3.75 |
Other male genitals | 10 | 1.03 | 0.49–1.91 | 7 | 0.58 | 0.23–1.21 | 9 | 0.65 | 0.29–1.24 |
Kidney | 83 | 0.78 | 0.62–0.97 | 82 | 0.76 | 0.60–0.94 | 86 | 0.69 | 0.55–0.84 |
Urinary bladder | 282 | 0.87 | 0.77–0.98 | 325 | 0.89 | 0.80–1.00 | 365 | 0.85 | 0.76–0.94 |
Melanoma | 175 | 0.70 | 0.60–0.81 | 158 | 0.72 | 0.61–0.84 | 205 | 0.74 | 0.64–0.85 |
Skin | 448 | 0.89 | 0.81–0.98 | 448 | 0.90 | 0.82–0.98 | 582 | 0.84 | 0.78–0.92 |
Eye | 11 | 0.80 | 0.40–1.43 | 7 | 0.55 | 0.22–1.14 | 12 | 0.72 | 0.37–1.27 |
Nervous system | 59 | 0.73 | 0.55–0.94 | 51 | 0.77 | 0.57–1.02 | 118 | 1.39 | 1.15–1.66 |
Thyroid gland | 16 | 0.66 | 0.38–1.07 | 16 | 0.79 | 0.45–1.29 | 22 | 0.82 | 0.51–1.24 |
Endocrine glands | 102 | 1.00 | 0.82–1.22 | 94 | 1.03 | 0.83–1.26 | 123 | 1.07 | 0.89–1.27 |
Connective tissue | 16 | 0.66 | 0.38–1.07 | 22 | 0.92 | 0.57–1.39 | 27 | 0.85 | 0.56–1.24 |
Non-Hodgkin's lymphoma | 164 | 0.73 | 0.62–0.85 | 147 | 0.70 | 0.59–0.83 | 227 | 0.82 | 0.72–0.93 |
Hodgkin's disease | 5 | 0.69 | 0.22–1.63 | 6 | 0.88 | 0.32–1.93 | 5 | 0.61 | 0.19–1.42 |
Myeloma | 37 | 0.76 | 0.54–1.05 | 34 | 0.71 | 0.49–0.99 | 53 | 0.84 | 0.63–1.09 |
Leukemia | 52 | 0.82 | 0.61–1.08 | 50 | 0.87 | 0.64–1.15 | 57 | 0.76 | 0.58–0.99 |
Smoking related# | 588 | 0.77 | 0.71–0.84 | 592 | 0.75 | 0.69–0.81 | 740 | 0.76 | 0.71–0.82 |
Non-smoking related | 3987 | 0.84 | 0.81–0.86 | 3565 | 0.78 | 0.76–0.81 | 4618 | 0.78 | 0.76–0.81 |
All | 4575 | 0.82 | 0.80–0.85 | 4157 | 0.78 | 0.75–0.80 | 5358 | 0.78 | 0.76–0.80 |
Adjusted for age, sex, education, birth country, period of dementia diagnosis, diabetes, and hypertension.
Defined as cancer of the oral, esophageal, stomach, pancreas, lung, cervix, kidney, and urinary bladder.
Bold values indicate SIR less than 1 and 95% CI does include 1.00.