TABLE 2.

Association of rs17125924 of FERMT2 with AD risk stratified by APOEε4 status.

	MAF	P allele	P genotype	Dominant	Recessive	Additive	Overdominant
		OR (95%CI)		P value	P value	P value	P value
				OR (95%CI)	OR (95%CI)	OR (95%CI)	OR (95%CI)
Total	0.293/0.249	0.149	0.021	0.022	0.353	0.141	0.005
		1.252		1.57	1.45	1.27	1.76
		(0.92–1.70)		(1.07–2.32)	(0.67–3.15)	(0.93–1.73)	(1.18–2.61)
ApoE ε4(+)	0.350/0.221	0.029	0.036	0.009	0.762	0.03	0.015
		1.895		2.74	1.24	2.02	2.66
		(1.06–3.38)		(1.28–5.86)	(0.31–4.90)	(1.07–3.82)	(1.21–5.85)
ApoE ε4(-)	0.230/0.256	0.503	0.028	0.757	0.039	0.508	0.15
		0.869		1.08	0.12	0.87	1.45
		(0.58–1.31)		(0.66–1.78)	(0.02–0.90)	(0.57–1.32)	(0.87–2.41)

AD, Alzheimer’s disease; Allele, minor allele; MAF, minor allele frequency; OR, odds ratio; CI, confidence interval. Dominant was defined as 1 (aa + Aa) versus 0 (AA). Recessive was defined as 1 (aa) versus 0 (AA + Aa), and additive was defined as 0 (AA) versus 1 (Aa) versus 2 (aa). Overdominant was defined as 1 (Aa) versus 0 (AA + aa). (A: major allele; a: minor allele). P allele and P genotype were examined using the Chi-square test. P value was adjusted for gender and age with binary logistic regression. Bold indicates statistically significant values.