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. 2020 Feb 10;10:2262. doi: 10.1038/s41598-020-59057-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The network of SETD3, FOXM1, FBXW7, ACTB (β-actin), Fascin, MMP-2, KLC4, iNOS, and eNOS interactors. (A) STRING database output depicting functional and physical interactors of SETD3, FOXM1, FBXW7, ACTB, and Fascin obtained from http://string-db.org/. The analyzed proteins are highlighted in red boxes. (B) GO (gene ontology) analysis of SETD3, FOXM1, FBXW7, ACTB (β-actin), Fascin, MMP-2, KLC4, iNOS, and eNOS. The 10 most significantly (p < 0.05) enriched GO terms in molecular function (yellow), cellular component (orange), and biological process (red) branches are presented. (C) KEGG pathway analysis. All the adjusted statistically significant values of the terms were negative 10-base log-transformed.