Table 1.

Correlation between the expression of SETD3 and the status of breast cancer patients according to different classifications.

Classification	status	Cases	HR 95% CI	P value
ALL		3951	0.8 (0.71–0.89)	4.3e-05
Estrogen receptor (ER)	Positive (+)	3082	0.85 (0.75–0.97)	0.012
	Negative (−)	869	1.03 (0.83–1.27)	0.79
Progesterone receptor (PR)	Positive	589	1.29 (0.9–1.82)	0.16
	Negative	549	1.4 (1.04–1.88)	0.026
Her2	Positive	252	1.15 (0.75–1.78)	0.52
	Negative	800	1.15 (0.88–1.49)	0.31
ER, PR, Her2	Negative	196	1.72 (1.04–2.83)	0.031
Intrinsic subtype	Luminal A	1933	0.75 (0.66–0.93)	0.0049
	Luminal B	1149	1.01 (0.84–1.23)	0.89
	Her2	251	1.1 (0.75–1.62)	0.62
	Basal	618	1.01 (0.79–1.3)	0.91
Lymph node	Positive	1133	1.04 (0.86–1.27)	0.68
	Negative	2020	0.97 (0.82–1.15)	0.74
Grade	1	345	0.81 (0.48–1.36)	0.42
	2	901	0.98 (0.77–1.25)	0.87
	3	903	1.11 (0.89–1.37)	0.37
p53	Mutated	188	2.1 (1.29–3.44)	0.0024
	Wild type	273	0.95 (0.63–1.45)	0.82
p53 mutated	ER+	87	2.93 (1.47–5.85)	0.0014
	ER-	101	1.46 (0.72–2.93)	0.29
	PR+	25	11.23 (1.42–88.83)	0.0039
	PR-	50	2.15 (0.86–5.4)	0.95
	Luminal A	164	2.35 (0.8–6.88)	0.11
	Luminal B	55	2.42 (1.01–5.79)	0.041
p53 wild type	ER+	251	0.94 (0.61–1.46)	0.8
	ER-	22	1.88 (0.34–10.37)	0.46
	PR+	52	3.18 (0.87–11.65)	0.065
	PR-	24	0.77 (0.2–2.87)	0.69
	Luminal A	32	0.89 (0.5–1.59)	0.69
	Luminal B	87	0.91 (0.47–1.76)	0.77