Table 4.
Associations between anthropometric measures and risk of breast cancer stratified by tumour subtype.
| Estrogen receptor positive | Estrogen receptor negative | Triple negative | ||||
|---|---|---|---|---|---|---|
| Cases/controls | ORa (95% CI) | Cases/controls | ORa (95% CI) | Cases/controls | ORa (95% CI) | |
| Height, per 10 cm | 203/203 | 1.06 (0.68–1.66) | 81/81 | 1.03 (0.45–2.39) | 61/61 | 1.09 (0.32–3.78) |
| Leg length, per 10 cm | 202/202 | 0.93 (0.50–1.72) | 79/79 | 1.01 (0.33–3.10) | 60/60 | 1.02 (0.26–3.96) |
| Weight, per 10 kg | 203/203 | 0.83 (0.66–1.03) | 81/81 | 0.60 (0.39–0.92) | 61/61 | 0.63 (0.32–1.26) |
| Waist circumference, per 10 cm | 202/202 | 0.97 (0.75–1.26) | 80/80 | 0.73 (0.47–1.13) | 60/60 | 1.18 (0.58–2.39) |
| Hip circumference, per 10 cm | 202/202 | 0.86 (0.65–1.12) | 80/80 | 0.73 (0.44–1.19) | 60/60 | 2.27 (0.76–6.81) |
| BMI, per 1 kg/m2 | 203/203 | 0.95 (0.90–1.01) | 81/81 | 0.90 (0.82–0.99) | 61/61 | 0.92 (0.79–1.06) |
| Waist-to-hip ratio, per 0.1 unit | 202/202 | 1.37 (0.85–2.20) | 80/80 | 0.68 (0.27–1.69) | 60/60 | 0.63 (0.19–2.09) |
Abbreviations: BMI, body mass index; CI, confidence interval; OR, odds ratio.
aOdds ratios were estimated by logistic regression conditioned on age (±3 years), city district of residence, and health insurance institution and adjusted for education (≤primary/secondary/> secondary), history of benign breast disease (yes/no), family history of breast cancer (yes/no), total physical activity (tertiles), number of full-term pregnancies (0/1/≥2), age at first full-term pregnancy (tertiles/nulliparous/missing), cumulated duration of breastfeeding (</≥12 months), age at menarche (</≥12 years old), smoking status (current/former/never), diabetes (yes/no), daily alcohol intake (tertiles/non-consumer). Except for height and leg length, all models were additionally adjusted for height (tertiles).