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. 2020 Feb 10;8:6. doi: 10.1038/s41413-019-0077-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 11 — Schematic diagram illustrating the anti-inflammatory and chondroprotective effects of TWC in cell and rat models of OA. The middle section shows the process of TWC synthesis. The upper section shows the TWC-mediated attenuation of chondrocyte inflammation in the OA cell model. The lower section shows the TWC-mediated alleviation of OA in the rat model