Table 1.
No. that met criteria (n = 96) | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Parameter | P value | Relative risk | 95% CI | Sens | Spec | PPV | NPV | AUC | Criteria | Cured | Fail | Recur |
TGAI change M6 | < 0.0001 | 6.97 | 2.53–19.22 | 0.80 | 0.75 | 0.46 | 0.94 | 0.80 | < 80% | 19 | 7 | 9 |
TGAIcom change M6 | < 0.0001 | 6.67 | 2.42–18.40 | 0.80 | 0.74 | 0.44 | 0.93 | 0.80 | 80% | 20 | 7 | 9 |
Cavity M6 | < 0.001 | 4.36 | 2.09–9.12 | 0.55 | 0.86 | 0.52 | 0.88 | 0.65 | > 7 ml | 10 | 7 | 4 |
Cav change M6 | < 0.01 | 4.30 | 1.91–9.64 | 0.65 | 0.79 | 0.45 | 0.90 | 0.68 | < 60% | 16 | 6 | 7 |
M6 TGAIcom | < 0.001 | 4.05 | 1.98–8.32 | 0.50 | 0.88 | 0.52 | 0.87 | 0.68 | > 1000 | 9 | 6 | 4 |
TGAI M6 | < 0.001 | 4.05 | 1.98–8.33 | 0.50 | 0.88 | 0.53 | 0.87 | 0.69 | > 600 | 9 | 6 | 4 |
Cavwall M6 | 0.00 | 3.95 | 1.90–7.90 | 0.50 | 0.88 | 0.53 | 0.87 | 0.70 | ≥ 3 mm | 9 | 6 | 4 |
Mixed response M6 | 0.02 | 2.86 | 1.30–6.31 | 0.60 | 0.72 | 0.36 | 0.87 | N/A | Intensified | 21 | 8 | 4 |
Vtotal M6 | 0.05 | 2.20 | 1.03–4.56 | 0.45 | 0.77 | 0.35 | 0.84 | 0.64 | > 7% | 17 | 6 | 3 |
SUVmax M6 | 0.19 | 1.82 | 0.85–3.85 | 0.50 | 0.68 | 0.29 | 0.84 | 0.60 | > 4 | 24 | 6 | 4 |
Cav change M1 | 0.01 | 2.80 | 1.33–5.92 | 0.50 | 0.80 | 0.40 | 0.86 | 0.52 | < 33% | 15 | 5 | 5 |
Cavity M1 | 0.04 | 2.50 | 1.18–5.32 | 0.35 | 0.87 | 0.41 | 0.84 | 0.57 | > 20 mm3 | 10 | 6 | 1 |
TGAI change M1 | 0.07 | 2.24 | 1.05–4.78 | 0.40 | 0.82 | 0.36 | 0.84 | 0.67 | < 5% | 14 | 4 | 4 |
TGAIcom change M1 | 0.16 | 1.80 | 0.83–3.89 | 0.40 | 0.76 | 0.31 | 0.83 | 0.66 | 15% | 18 | 3 | 5 |
Vtotal change M6 | 0.01 | 2.89 | 1.39–5.77 | 0.40 | 0.87 | 0.44 | 0.85 | 0.66 | < 50% | 10 | 5 | 3 |
Cavity Dx | 0.18 | 1.72 | 0.79–3.71 | 0.45 | 0.72 | 0.29 | 0.83 | 0.53 | > 16.5 ml | 22 | 6 | 3 |
Ranked according to relative risk of unfavourable outcome. Fisher exact test was performed to determine significance. Sens (sensitivity), spec (specificity), PPV (positive predictive value), NPV negative predictive value. Change (change from baseline), intensified (at least one intensified or new lesion), month 6 (M6), percentage change from baseline to M6 (change), total glycolytic activity index (TGAI), composite TGAI (TGAIcom), cavity wall thickness (Cavwall), total abnormal density volume (Vtotal)