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. 2020 Jan 23;106(2):188–201. doi: 10.1016/j.ajhg.2020.01.003

Figure 2.

Figure 2

Transcriptome-wide Association Studies of 46 Metabolites across 43 Tissues

(A) Manhattan plot showing all S-PrediXcan associations across 46 metabolites in all 43 tissues analyzed, with each point representing a gene-metabolite association. Labels indicate loci where TWAS associations involve high-confidence causal genes. The y axis shows the negative log10 p values from the S-PrediXcan association test.

(B) Bar plot of the number of significant gene-metabolite associations observed per tissue.