Table 3.

Effect of nHA, nCh/HA and nAg/HA as well as ALN on RANKL and CtsK gene expression levels in osteoporotic rats.

Groups	Relative RANKL gene expression	Relative CtsK gene expression
Gonad-intact control	1.06 ± 0.15	1.03 ± 0.09
Osteoporotic	1.81 ± 0.066*a (70.16%)	1.88 ± 0.19*a (82.97%)
nHA	0.89 ± 0.039*b (-50.23%)	0.55 ± 0.054*b (-70.73%)
nCh/HA	0.94 ± 0.04*b (-48.14%)	0.63 ± 0.024*b (-66.36%)
nAg/HA	1.18 ± 0.038*b*c*d (-34.89%)	0.67 ± 0.022*b (-64.20%)
ALN	1.2 ± 0.053*b*c*d (-26.67%)	0.71 ± 0.035*b (-62.74%)

Data are expressed as Mean ± S.E for 8 rats/group.

*a: Significant change at P < 0.05 in comparison with the gonad-intact group.

*b: Significant change at P < 0.05 in comparison with the osteoporotic group.

*c: Significant change at P < 0.05 in comparison with the nHA-treated group.

*d: Significant change at P < 0.05 in comparison with the nCh/HA-treated group.