Table 3.

Difference in weight and BMI from baseline to ~ 50-week follow-up among intervention vs. control participants in the BWHealthy Weight Study†

	Model 1		Model 2		Model 3		Model 4
	β (95% CI)	p-value	β (95% CI)	p-value	β (95% CI)	p-value	β (95% CI)	p-value
Outcome
Difference baseline to follow-up, for intervention vs. control participants*
Difference in weight, kg	−0.84 (−4.31, 2.63)	0.63	−1.17 (−4.97, 2.63)	0.54	−1.25 (−5.10, 2.61)	0.52	−1.12 (−5.28, 3.05)	0.59
Difference in BMI, kg/m2	−0.34 (−1.55, 0.87)	0.57	−0.46 (−1.77, 0.86)	0.49	−0.46 (−1.79, 0.88)	0.49	−0.48 (−1.93, 0.96)	0.50
Sensitivity**
Difference in weight, kg	−0.86 (−4.79, 3.06)	0.66	−0.93 (−5.27, 3.41)	0.66	−0.95 (−5.36, 3.46)	0.66	−0.58 (−5.39, 4.22)	0.81
Difference in BMI, kg/m2	−0.36 (−1.72, 1.01)	0.60	−0.38 (−1.88, 1.13)	0.61	−0.38 (−1.91, 1.15)	0.62	−0.35 (−2.04, 1.33)	0.67

*For participants who withdrew from the study before the completion of 50 weeks, the last weigh-in value for each participant was carried forward (N = 5; 4 intervention, 1 control).

**Excluded participants who withdrew from the study before the completion of 50 weeks (N = 5).

Model 1. Unadjusted linear regression

Model 2. Adjusted for age, sex, race/ethnicity, and time elapsed from baseline to follow-up (weeks)

Model 3. Model 2 additionally adjusted for baseline weight (for weight outcomes) or baseline BMI (for BMI outcomes)

Model 4. Model 3 additionally adjusted for weight loss in the prior 2 years and time elapsed from max weight in prior 2 years to enrollment date. One participant was missing max weight loss in the prior two years; we used the validated max weight loss in one year prior.

†Data collected from Brigham and Women’s Hospital employees in Boston, MA between 2016 and 2018.