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. 2020 Jan 14;24(3):2284–2293. doi: 10.1111/jcmm.14911

Figure 4.

Figure 4

IL‐6 was involved in the regulation of cytokine profile of THP‐1–derived macrophages by poly(I:C)‐treated cervical cancer cells. THP‐1–derived macrophages were treated with CM of cervical cancer cells, which was pre‐treated by control or IL‐6 siRNA, with/without poly(I:C) stimulation. mRNA level (A) and supernatant concentration (B) of IL‐1β, IL‐6, IL‐10 and CCL22 were measured. The RT‐PCR data were normalized to the control and shown as fold change. Each bar represents mean ± SD (n = 3. *P < .05; **P < .01.)