Figure 1.

Ischaemia up‐regulates Prrx2 and Wnt5a gene expressions in mice following MI. Male Apoe^−/− mice were subjected to perform MI surgery and hearts were isolated from mice at the 30th post‐operative days to detect (A) gene expressions of Prrx2, Wnt5a, α‐SMA, GAPDH, collagen I (Col I) and collagen III (Col III) by real‐time PCR. B and C, Protein levels of Prrx2, Wnt5a, α‐SMA, GAPDH, collagen I and collagen III in heart homogenates were determined by Western blotting in B and quantitative analysis was performed in C. N is 10‐15 in each group. *P < .05 vs Sham