Table 1.

Data sources for base case and sensitivity analyses

Inputs	Base case	Sensitivity analysis
Risk of developing CHF	Based on risk scores and the standard model risk equations developed by Chow et al. [13]	Based on the Hazard ratio for CHF in a cohort of adult survivors of childhood and adolescent cancer according to anthracycline dose [16]
Extrapolation of cumulative CHF incidence	Polynomial	Linear
Risk of dying from non-CHF causes	Based on cause-specific cumulative mortality curves developed by Mertens et al. [20]	Based on life tables combined with SMR [21]
Treatment effect calculations	Based on meta-analysis of data from non-randomized and randomized studies using M–H approach	Based on Bayesian meta-analysis of data from non-randomized and randomized studies
Utility values	As presented in Wong et al. [22]	Based on New York Heart Association classes I and III, [0.855 (0.845; 0.846) and 0.673 (0.665; 0.690)] representing heath states ALVD and CHF respectively [23]

ALVD asymptomatic left ventricular dysfunction, CHF congestive heart failure, SMR standardised mortality ratio