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Unaltered AMPK activation and cathepsin B (CatB) expression in skeletal muscle of exercise-trained 3xTg-AD mice. (a) Immunoblots for CatB, p-AMPK, and AMPK in skeletal muscle homogenate. (b) CatB expression normalized to β-actin. (c) p-AMPK expression normalized to total AMPK. Data presented as mean ± SE. Tissues assayed from the nonexercised group (Tg), the aerobic-trained group (Tg+AT), or the resistance-trained group (Tg+RT) (n = 10/group). Differences determined by one-way ANOVA.
