Table 2.
Plasma small RNA classes in patients with RA and control subjectsa
| sRNA Class | RA (N = 165) | Control (N = 90) | Fold Difference | P |
|---|---|---|---|---|
| miRNA | 100 814 (86 923, 116 925) | 70 982 (57 236, 88 029) | 1.42 | 0.01 |
| yDR | 185 245 (159 332, 215 372) | 260 447 (217 449, 311 947) | −1.41 | 0.009 |
| tDR | 2690 (2399, 3017) | 2370 (1876, 2995) | 1.14 | 0.04 |
| rDR | 10 772 (9319, 12 451) | 9521 (7473, 12 130) | 1.13 | 0.21 |
| lncDR | 708 (615, 815) | 810 (623, 1053) | −1.14 | 0.67 |
| snDR | 311 (267, 363) | 344 (277, 427) | −1.11 | 0.39 |
| snoDR | 56 (47, 66) | 49 (37, 64) | 1.14 | 0.22 |
| miscRNA | 108 (89, 130) | 79 (63, 99) | 1.37 | 0.06 |
Abbreviation: lncRNA, long noncoding RNA–derived small RNA; miRNA, microRNA; miscRNA, miscellaneous RNA; RA, rheumatoid arthritis; rDR, ribosomal RNA–derived small RNA; snDR, small nuclear RNA–derived small RNA; snoDR, small nucleolar RNA–derived small RNA; tDR, transfer RNA–derived small RNA; yDR, Y RNA–derived small RNA.
a
Data are presented as the geometric mean with 95% confidence intervals of the geometric mean due to skewness of the data.