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. Author manuscript; available in PMC: 2020 Nov 5.
Published in final edited form as: Anal Chem. 2019 Oct 9;91(21):13485–13493. doi: 10.1021/acs.analchem.9b02483

Figure 4.

Figure 4.

Pattern recognition in the 2-tiered topochemical analyses for miRNAs. Binding of individual targets is recognized in the RF vs ΔL plot of either the 1st (Tier 1) or the 2nd (Tier 2) unfolding feature of individual F-X curves. Green and pink depict without and with miRNA targets, respectively. Ellipses indicate the data range at 95% confidence level without target.