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. 2020 Feb 10;12:24. doi: 10.1186/s13148-020-0818-7

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — H3K27me3 expression compared between primary melanomas and cutaneous melanoma metastases. a H3K23me3 expressing tumors (in %) comparing primary melanomas (n = 136) and cutaneous melanoma metastases (n = 84). Significance was determined by Χ² test for categorical data. b H3K27me3 IHC staining of primary melanomas and cutaneous melanoma metastases in 5-fold and 40-fold magnification (from left to right). Cutaneous melanoma metastases show a more frequent expression of H3K27me3 in comparison to primary melanomas.