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. 2020 Feb 10;17:6. doi: 10.1186/s12981-020-0262-y

Table 4.

Comparison to RAMs combinations decreasing response to dolutegravir in the VIKING-3 study

RAMs combinations after RAL use Prevalence (%)
VIKING-3 [15] This study
No INSTIs mutations 33 48
No Q148a 36 40
Q148 + 1 secondary mutationb 20 8
Q148 + ≥2 secondary mutationsb 11 4

RAMs resistance associated mutations, RAL raltegravir, INSTIs integrase strand transfer inhibitors

aY143, N155, T66 or E92

bG140A/C/S, L74I or E138A/K/T