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. 2020 Feb 10;19:16. doi: 10.1186/s12933-020-0995-x

Table 2.

Associations between cardiac adipose tissue and clinical characteristics as well as measures of cardiac function

Controls
(n = 30)
Persons with type 1 diabetes
(n = 60)
Persons with type 2 diabetes
(n = 60)
β coefficient (95% CI) p β coefficient (95% CI) p β coefficient (95% CI) p
Clinical characteristics
 Age 0.007 (0.001; 0.013) 0.02 0.003 (− 0.0001; 0.006) 0.06 0.001 (− 0.001; 0.004) 0.27
 Body mass index 0.034 (0.017; 0.052) 0.0004 0.039 (0.029; 0.049) < 0.0001 0.014 (0.003; 0.026) 0.02
 LDL cholesterol 0.00006 (− 0.006; 0.007) 0.99 0.002 (− 0.001; 0.005) 0.20 0.002 (− 0.0008; 0.004) 0.17
 Total cholesterol − 0.001 (− 0.008; 0.005) 0.66 0.002 (− 0.001; 0.006) 0.19 0.002 (− 0.0008; 0.004) 0.16
 Lipid lowering treatment − 0.00005 (− 0.002; 0.001) 0.95 0.0001 (− 0.0005; 0.0008) 0.68
 Hemoglobin A1c 0.0002 (− 0.004; 0.009) 0.46 − 0.0003 (− 0.004; 0.003) 0.84 0.001 (− 0.001; 0.003) 0.37
 Urinary albumin excretion ratea 0.006 (0.0005; 0.012) 0.03 0.002 (− 0.002; 0.005) 0.31 0.0016 (− 0.001; 0.004) 0.38
 Systolic blood pressure 0.005 (− 0.002; 0.011) 0.14 0.002 (− 0.002; 0.005) 0.29 0.0007 (− 0.002; 0.003) 0.60
Cardiac measures
 Left ventricle ejection fraction − 0.004 (− 0.01; 0.003) 0.23 − 0.003 (− 0.006; 0.0003) 0.08 0.0005 (− 0.002; 0.003) 0.72
 Coronary artery calcium score 0.008 (0.002; 0.013) 0.008 0.001 (− 0.002; 0.005) 0.50 − 0.0002 (− 0.003; 0.003) 0.89
 Myocardial flow reserve − 0.008 (− 0.014; − 0.003) 0.005 − 0.0007 (− 0.004; 0.003) 0.67 0.00002 (− 0.003; 0.003) 0.98
 Late heart-to-mediastinum ratiob − 0.009 (− 0.022; 0.003) 0.12 − 0.002 (− 0.006;0.001) 0.19 0.001 (− 0.003; 0.005) 0.59

Linear regression analysis. The three groups were analyzed separately. β coefficient represents standardized effects within groups

Italic values indicate significance of p value (p < 0.05)

aUrinary albumin creatinine rate for the persons with type 1 diabetes

bAvailable in 14 controls, 29 persons with type 2 diabetes and 60 persons with type 1 diabetes