Table 2.
Associations between cardiac adipose tissue and clinical characteristics as well as measures of cardiac function
| Controls (n = 30) |
Persons with type 1 diabetes (n = 60) |
Persons with type 2 diabetes (n = 60) |
||||
|---|---|---|---|---|---|---|
| β coefficient (95% CI) | p | β coefficient (95% CI) | p | β coefficient (95% CI) | p | |
| Clinical characteristics | ||||||
| Age | 0.007 (0.001; 0.013) | 0.02 | 0.003 (− 0.0001; 0.006) | 0.06 | 0.001 (− 0.001; 0.004) | 0.27 |
| Body mass index | 0.034 (0.017; 0.052) | 0.0004 | 0.039 (0.029; 0.049) | < 0.0001 | 0.014 (0.003; 0.026) | 0.02 |
| LDL cholesterol | 0.00006 (− 0.006; 0.007) | 0.99 | 0.002 (− 0.001; 0.005) | 0.20 | 0.002 (− 0.0008; 0.004) | 0.17 |
| Total cholesterol | − 0.001 (− 0.008; 0.005) | 0.66 | 0.002 (− 0.001; 0.006) | 0.19 | 0.002 (− 0.0008; 0.004) | 0.16 |
| Lipid lowering treatment | – | – | − 0.00005 (− 0.002; 0.001) | 0.95 | 0.0001 (− 0.0005; 0.0008) | 0.68 |
| Hemoglobin A1c | 0.0002 (− 0.004; 0.009) | 0.46 | − 0.0003 (− 0.004; 0.003) | 0.84 | 0.001 (− 0.001; 0.003) | 0.37 |
| Urinary albumin excretion ratea | 0.006 (0.0005; 0.012) | 0.03 | 0.002 (− 0.002; 0.005) | 0.31 | 0.0016 (− 0.001; 0.004) | 0.38 |
| Systolic blood pressure | 0.005 (− 0.002; 0.011) | 0.14 | 0.002 (− 0.002; 0.005) | 0.29 | 0.0007 (− 0.002; 0.003) | 0.60 |
| Cardiac measures | ||||||
| Left ventricle ejection fraction | − 0.004 (− 0.01; 0.003) | 0.23 | − 0.003 (− 0.006; 0.0003) | 0.08 | 0.0005 (− 0.002; 0.003) | 0.72 |
| Coronary artery calcium score | 0.008 (0.002; 0.013) | 0.008 | 0.001 (− 0.002; 0.005) | 0.50 | − 0.0002 (− 0.003; 0.003) | 0.89 |
| Myocardial flow reserve | − 0.008 (− 0.014; − 0.003) | 0.005 | − 0.0007 (− 0.004; 0.003) | 0.67 | 0.00002 (− 0.003; 0.003) | 0.98 |
| Late heart-to-mediastinum ratiob | − 0.009 (− 0.022; 0.003) | 0.12 | − 0.002 (− 0.006;0.001) | 0.19 | 0.001 (− 0.003; 0.005) | 0.59 |
Linear regression analysis. The three groups were analyzed separately. β coefficient represents standardized effects within groups
Italic values indicate significance of p value (p < 0.05)
aUrinary albumin creatinine rate for the persons with type 1 diabetes
bAvailable in 14 controls, 29 persons with type 2 diabetes and 60 persons with type 1 diabetes